Search Result
Results for "
self-assembling peptide
" in MedChemExpress (MCE) Product Catalog:
2
Biochemical Assay Reagents
| Cat. No. |
Product Name |
Target |
Research Areas |
Chemical Structure |
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- HY-W441011
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Liposome
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Neurological Disease
Inflammation/Immunology
Cancer
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DSPE-NHS is a bioconjugation phospholipid molecule with two hydrophobic lipid tails. DSPE-NHS is a self-assembling reagent which forms lipid bilayer in aqueous solution. The NHS-ester is reactive with N-terminal of protein/peptide or other amine molecule to form a stable amide linkage. DSPE-NHS labels antibodies. DSPE-NHS can be used to prepare liposomes as agent nanocarrier .
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- HY-P10294
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Amyloid-β
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Others
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Oligopeptide P11-4 is an α-peptide that can be self-assembled into β-sheet amyloids with a hydrogel appearance at low pH. Oligopeptide P11-4 can be used in biomimetic mineralization, enamel regeneration and oral care agent .
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- HY-P10709A
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Biochemical Assay Reagents
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Cardiovascular Disease
Cancer
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CREKA peptide acetate is a short peptide sequence, belonging to self-assembling peptides (SAPs), which can self-assemble into functional nanostructures, typically nanofibers, under physiological conditions. CREKA peptide acetate can be used to target tumor cells and tumor vasculature, exhibiting antitumor activity .
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- HY-P2632
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RADA16
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Biochemical Assay Reagents
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Neurological Disease
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RAD16-I (RADA16) is a non-directed self-assembling peptide hydrogel. Under physiological conditions, RAD16-I spontaneously forms a three-dimensional nanofiber network that mimics the extracellular matrix, and possesses excellent properties such as high water content, biocompatibility and degradability. RAD16-I serves as an ideal scaffold for three-dimensional cell culture. RAD16-I not only maintains cell viability and induces self-organization, but also supports cell adhesion, proliferation, differentiation and insulin secretion, effectively stabilizes islet clusters and promotes directed differentiation of the cardiac lineage. RAD16-I can construct a cell-friendly nano-microenvironment for research related to diseases such as myocardial infarction and diabetes .
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- HY-P10659
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EGFR
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Cancer
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Self-assembling peptide pY1 is a peptide that assemblies around cancer cells and targets EGFR. When co-cultured with Ovalbumin (OVA), pY1 can effectively block the endocytosis of OVA .
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- HY-P10699
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- HY-P10701
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Biochemical Assay Reagents
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Inflammation/Immunology
Cancer
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Q11 peptide is a β-sheet-forming peptide that plays an important role in self-assembly and targeted applications. As a scaffold peptide, Q11 peptide can display immunogenic epitopes and is widely used in peptide-based immune vaccine research. Additionally, Q11 peptide can be conjugated with MUC1 glycopeptides for the study of self-assembling, adjuvant-free MUC1 glycopeptide vaccines. Q11 peptide holds great potential for research in the field of cancer immunology .
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- HY-P11309
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Biochemical Assay Reagents
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Neurological Disease
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QL6 peptide is a self-assembling peptide. QL6 peptide can self-assembles into β-sheets bridging the cavity at neutral pH and improves the inhibitory environment by reducing inflammation and tissue scaring. QL6 peptide can be used for synthesis nanofiber scaffolds for spinal cord injuries (SCI) research .
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- HY-P10712
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- HY-P10675
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Biochemical Assay Reagents
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Metabolic Disease
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Peptide K is a self-assembling peptide fiber that can be used to prepare fibrous nanocomposite hydrogels. The fibrous nanocomposite hydrogels have a dynamic network that adapts to cells and enhances cell-matrix and cell-cell interactions, thus significantly promoting the mechanotransduction, metabolic energy, and osteogenesis of encapsulated stem cells .
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- HY-P10706
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- HY-P10686
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EGFR
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Cancer
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CH401 peptide is a HER2-derived antigen peptide. After being bound to the artificial viral capsid by a self-assembled β-cyclic peptide, CH401 peptide is encapsulated in a lipid bilayer containing the lipid adjuvant α-GalCer, and can be studied as a self-adjuvant anti-breast cancer vaccine candidate .
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- HY-P11055
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Bacterial
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Infection
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IKFQFHFD is a pH-responsive and self-assembling peptide. IKFQFHFD is biocompatible at neutral pH and becomes an antimicrobial peptide-like molecular structure only at acidic pH. IKFQFHFD can be used for chronic wounds (venous ulcers, diabetic ulcers, and pressure ulcers) induced by biofilm infections research .
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- HY-141460
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Ile-Ala; L-Isoleucyl-L-alanine
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Biochemical Assay Reagents
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Others
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H-Ile-Ala-OH (Ile-Ala; L-Isoleucyl-L-alanine) is a linear aliphatic dipeptide and self-reactive cyclization reagent that self-assembles into amorphous films or spherical structures from specific solvents. H-Ile-Ala-OH also serves as a precursor for the synthesis of the cyclic peptide cyclo (L-isoleucyl-L-alanine) (HY-N9251). H-Ile-Ala-OH undergoes solid-state cyclization when heated above 206 °C, and its initiation temperature is closely related to the size of side-chain substituents .
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- HY-P10705
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Biochemical Assay Reagents
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Cancer
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KGFRWR is a short peptide sequence, belonging to self-assembling peptides (SAPs), which can self-assemble into functional nanostructures, typically nanofibers, under physiological conditions. KGFRWR can be used to target tumor cells and tumor vasculature, exhibiting antitumor activity .
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- HY-P6079A
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Biochemical Assay Reagents
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Others
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Ac-IHIHIYI-NH2 TFA is an amyloid self-assembling peptide variant that can be used as a bioactive nanomaterial with esterase activity .
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- HY-P10702
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Biochemical Assay Reagents
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Others
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SAF-p1 is a self-assembling fiber peptide that can form sticky-ended heterodimers by assembling with SAF-p2 (HY-P10703) through complementary amino acid sequences. These heterodimers further self-assemble into long-chain fiber structures. SAF-p1 is promising for the development of nanomaterials in the biomedical field .
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- HY-P10703
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Biochemical Assay Reagents
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Others
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SAF-p2 is a self-assembling fiber peptide that can form sticky-ended heterodimers by assembling with SAF-p2 (HY-P10702) through complementary amino acid sequences. These heterodimers further self-assemble into long-chain fiber structures. SAF-p2 is promising for the development of nanomaterials in the biomedical field .
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- HY-156087G
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Apoptosis
Necroptosis
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Cancer
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Cholicamideβ (GMP) is a GMP grade of Cholicamideβ. Cholicamideβ (compound 6) is a self-assembling, small molecule, cancer vaccine adjuvant. Cholicamideβ can form virus-like particles with low cytotoxicity. Cholicamideβ, upon binding to peptide antigens, enhances antigen presentation by dendritic cells and induces antigen-specific T cells. Cholicamideβ can induce apoptosis and necrosis .
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- HY-156087
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Apoptosis
Necroptosis
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Cancer
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Cholicamideβ (GMP) is a GMP grade of Cholicamideβ. Cholicamideβ (compound 6) is a self-assembling, small molecule, cancer vaccine adjuvant. Cholicamideβ can form virus-like particles with low cytotoxicity. Cholicamideβ, upon binding to peptide antigens, enhances antigen presentation by dendritic cells and induces antigen-specific T cells. Cholicamideβ can induce apoptosis and necrosis .
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- HY-149865
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Phosphatase
Fluorescent Dye
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Cancer
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TPE-1p is a cascade-activated AIEgen-peptide probe. TPE-1p self-assembles in aqueous solution to exhibit bright fluorescence in response to alkaline phosphatase (ALP) and ChT-L. TPE-1p can be utilized to noninvasively assess the inhibition efficiency of a ChT-L inhibitor in cells .
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- HY-P11468
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Bacterial
Antibiotic
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Cardiovascular Disease
Infection
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wkwkwNGwkwkw-NH2 is a self-assembling β-hairpin antimicrobial peptide. wkwkwNGwkwkw-NH2 self-assembles into nanofibers. wkwkwNGwkwkw-NH2 interacts with LPS on the surface of the bacterial membrane and then disrupts the bacterial outer membrane, inner membrane, and cytoplasmic membrane to exert its antibacterial effects. wkwkwNGwkwkw-NH2 has high antibacterial activity and low hemolytic activity. wkwkwNGwkwkw-NH2 significantly reduces the S. aureus ATCC 25923 load at the skin wound. wkwkwNGwkwkw-NH2 displays synergistic effects when combined with antibiotics. wkwkwNGwkwkw-NH2 facilitates wound healing .
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- HY-P2632C
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Biochemical Assay Reagents
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Neurological Disease
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RAD16-I, free acid TFA is a derivative of RADA16 (HY-P2632), with no Ac and NH2 modifications at both ends, and it has the same function as RADA16. RAD16-I, free acid TFA is a non-directed self-assembling peptide hydrogel. Under physiological conditions, RAD16-I, free acid TFA spontaneously forms a three-dimensional nanofiber network that mimics the extracellular matrix, and possesses excellent properties such as high water content, biocompatibility and degradability. RAD16-I, free acid TFA serves as an ideal scaffold for three-dimensional cell culture. RAD16-I, free acid TFA not only maintains cell viability and induces self-organization, but also supports cell adhesion, proliferation, differentiation and insulin secretion, effectively stabilizes islet clusters and promotes directed differentiation of the cardiac lineage. RAD16-I, free acid TFA can construct a cell-friendly nano-microenvironment for research related to diseases such as myocardial infarction and diabetes .
|
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-
- HY-P11794
-
|
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Collagen
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Others
|
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Type IV collagen peptide is a cell-binding ligand peptide derived from type IV collagen. (The sequence is TAGSCLRKFSTM) .
|
-
| Cat. No. |
Product Name |
Type |
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- HY-156087G
-
|
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Fluorescent Dye
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Cholicamideβ (GMP) is a GMP grade of Cholicamideβ. Cholicamideβ (compound 6) is a self-assembling, small molecule, cancer vaccine adjuvant. Cholicamideβ can form virus-like particles with low cytotoxicity. Cholicamideβ, upon binding to peptide antigens, enhances antigen presentation by dendritic cells and induces antigen-specific T cells. Cholicamideβ can induce apoptosis and necrosis .
|
| Cat. No. |
Product Name |
Type |
-
- HY-W441011
-
|
|
Biochemical Assay Reagents
|
|
DSPE-NHS is a bioconjugation phospholipid molecule with two hydrophobic lipid tails. DSPE-NHS is a self-assembling reagent which forms lipid bilayer in aqueous solution. The NHS-ester is reactive with N-terminal of protein/peptide or other amine molecule to form a stable amide linkage. DSPE-NHS labels antibodies. DSPE-NHS can be used to prepare liposomes as agent nanocarrier .
|
-
- HY-156087G
-
|
|
Biochemical Assay Reagents
|
|
Cholicamideβ (GMP) is a GMP grade of Cholicamideβ. Cholicamideβ (compound 6) is a self-assembling, small molecule, cancer vaccine adjuvant. Cholicamideβ can form virus-like particles with low cytotoxicity. Cholicamideβ, upon binding to peptide antigens, enhances antigen presentation by dendritic cells and induces antigen-specific T cells. Cholicamideβ can induce apoptosis and necrosis .
|
| Cat. No. |
Product Name |
Target |
Research Area |
-
- HY-P10294
-
|
|
Amyloid-β
|
Others
|
|
Oligopeptide P11-4 is an α-peptide that can be self-assembled into β-sheet amyloids with a hydrogel appearance at low pH. Oligopeptide P11-4 can be used in biomimetic mineralization, enamel regeneration and oral care agent .
|
-
- HY-P10709A
-
|
|
Biochemical Assay Reagents
|
Cardiovascular Disease
Cancer
|
|
CREKA peptide acetate is a short peptide sequence, belonging to self-assembling peptides (SAPs), which can self-assemble into functional nanostructures, typically nanofibers, under physiological conditions. CREKA peptide acetate can be used to target tumor cells and tumor vasculature, exhibiting antitumor activity .
|
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- HY-P2263
-
|
|
Peptides
|
Inflammation/Immunology
|
|
KLD-12 is a 12-residue self-assembling peptide that is used in tissue-engineering. KLD-12 combined with SDF-1 self-assembled polypeptide enhances chondrogenic differentiation of bone marrow stromal cells (BMSCs). KLD-12 hydrogel can fill full-thickness osteochondral defects in situ and improve cartilage repair .
|
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- HY-P2632
-
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RADA16
|
Biochemical Assay Reagents
|
Neurological Disease
|
|
RAD16-I (RADA16) is a non-directed self-assembling peptide hydrogel. Under physiological conditions, RAD16-I spontaneously forms a three-dimensional nanofiber network that mimics the extracellular matrix, and possesses excellent properties such as high water content, biocompatibility and degradability. RAD16-I serves as an ideal scaffold for three-dimensional cell culture. RAD16-I not only maintains cell viability and induces self-organization, but also supports cell adhesion, proliferation, differentiation and insulin secretion, effectively stabilizes islet clusters and promotes directed differentiation of the cardiac lineage. RAD16-I can construct a cell-friendly nano-microenvironment for research related to diseases such as myocardial infarction and diabetes .
|
-
- HY-P10659
-
|
|
EGFR
|
Cancer
|
|
Self-assembling peptide pY1 is a peptide that assemblies around cancer cells and targets EGFR. When co-cultured with Ovalbumin (OVA), pY1 can effectively block the endocytosis of OVA .
|
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- HY-P2632A
-
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RADA16 hydrochloride
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Peptides
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Neurological Disease
|
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RAD16-I hydrochloride, a soft nanofibrous self-assembling peptide, is a suitable microenvironment for human mesenchymal stem cells’ (hMSC) proliferation and differentiation into chondrocytes . RAD16-I is a well-studied ionic complementary peptide was used as a model to check potential amyloid-like staining properties of SAPNFs .
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- HY-P4054
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Peptides
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Others
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IEIK 13 is a self-assembling peptide (SAP) sequence. IEIK 13 can be used for the research of cartilage tissue engineering
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- HY-P10699
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- HY-P10701
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Biochemical Assay Reagents
|
Inflammation/Immunology
Cancer
|
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Q11 peptide is a β-sheet-forming peptide that plays an important role in self-assembly and targeted applications. As a scaffold peptide, Q11 peptide can display immunogenic epitopes and is widely used in peptide-based immune vaccine research. Additionally, Q11 peptide can be conjugated with MUC1 glycopeptides for the study of self-assembling, adjuvant-free MUC1 glycopeptide vaccines. Q11 peptide holds great potential for research in the field of cancer immunology .
|
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- HY-P11309
-
|
|
Biochemical Assay Reagents
|
Neurological Disease
|
|
QL6 peptide is a self-assembling peptide. QL6 peptide can self-assembles into β-sheets bridging the cavity at neutral pH and improves the inhibitory environment by reducing inflammation and tissue scaring. QL6 peptide can be used for synthesis nanofiber scaffolds for spinal cord injuries (SCI) research .
|
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- HY-P6299
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|
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Peptides
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Others
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MAX8 is a peptide made up of 20 residues that can fold and self-assemble under the influence of DMEM, forming a mechanically rigid hydrogel, this allows cells to be evenly immersed in the gel when the gelation is triggered in the presence of cells .
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- HY-P10712
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- HY-P10715
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Peptides
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Inflammation/Immunology
Cancer
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Fmoc-KCRGDK is a self-assembling peptide that can be used to prepare hydrogels and assist in drug delivery for immune checkpoint inhibitors. Fmoc-KCRGDK can be applied in cancer immunotherapy research .
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- HY-P10675
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Biochemical Assay Reagents
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Metabolic Disease
|
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Peptide K is a self-assembling peptide fiber that can be used to prepare fibrous nanocomposite hydrogels. The fibrous nanocomposite hydrogels have a dynamic network that adapts to cells and enhances cell-matrix and cell-cell interactions, thus significantly promoting the mechanotransduction, metabolic energy, and osteogenesis of encapsulated stem cells .
|
-
- HY-P10706
-
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- HY-P11067
-
|
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Peptides
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Others
|
|
PRG peptide is a self-assembling peptide. PRG peptide significantly enhances endothelial cell survival, proliferation, migration, and morphological tubulogenesis. PRG peptide can be used for tissue regeneration research .
|
-
- HY-P10686
-
|
|
EGFR
|
Cancer
|
|
CH401 peptide is a HER2-derived antigen peptide. After being bound to the artificial viral capsid by a self-assembled β-cyclic peptide, CH401 peptide is encapsulated in a lipid bilayer containing the lipid adjuvant α-GalCer, and can be studied as a self-adjuvant anti-breast cancer vaccine candidate .
|
-
- HY-P11055
-
|
|
Bacterial
|
Infection
|
|
IKFQFHFD is a pH-responsive and self-assembling peptide. IKFQFHFD is biocompatible at neutral pH and becomes an antimicrobial peptide-like molecular structure only at acidic pH. IKFQFHFD can be used for chronic wounds (venous ulcers, diabetic ulcers, and pressure ulcers) induced by biofilm infections research .
|
-
- HY-P2263A
-
|
|
Peptides
|
Inflammation/Immunology
|
|
KLD-12 TFA is the TFA salt form of KLD-12 (HY-P2263). KLD-12 TFA is a self a 12-residue self-assembling peptide that is used in tissue-engineering. KLD-12 TFA combined with SDF-1 self-assembled polypeptide enhances chondrogenic differentiation of bone marrow stromal cells (BMSCs). KLD-12 TFA hydrogel can fill full-thickness osteochondral defects in situ and improve cartilage repair .
|
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- HY-P11066
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|
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Peptides
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Others
|
|
RAD-FHR peptide is a self-assembling peptide. RAD-FHR peptide significantly enhances migration, proliferation and growth factor-secretion ability in human adipose stem cells (hASCs). RAD-FHR peptide can be used for synthesis of nanofiber hydrogel for stem cell behaviors research in biomimetic 3D systems .
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- HY-P10705
-
|
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Biochemical Assay Reagents
|
Cancer
|
|
KGFRWR is a short peptide sequence, belonging to self-assembling peptides (SAPs), which can self-assemble into functional nanostructures, typically nanofibers, under physiological conditions. KGFRWR can be used to target tumor cells and tumor vasculature, exhibiting antitumor activity .
|
-
- HY-P6079A
-
|
|
Biochemical Assay Reagents
|
Others
|
|
Ac-IHIHIYI-NH2 TFA is an amyloid self-assembling peptide variant that can be used as a bioactive nanomaterial with esterase activity .
|
-
- HY-P10702
-
|
|
Biochemical Assay Reagents
|
Others
|
|
SAF-p1 is a self-assembling fiber peptide that can form sticky-ended heterodimers by assembling with SAF-p2 (HY-P10703) through complementary amino acid sequences. These heterodimers further self-assemble into long-chain fiber structures. SAF-p1 is promising for the development of nanomaterials in the biomedical field .
|
-
- HY-P10703
-
|
|
Biochemical Assay Reagents
|
Others
|
|
SAF-p2 is a self-assembling fiber peptide that can form sticky-ended heterodimers by assembling with SAF-p2 (HY-P10702) through complementary amino acid sequences. These heterodimers further self-assemble into long-chain fiber structures. SAF-p2 is promising for the development of nanomaterials in the biomedical field .
|
-
- HY-P11068
-
|
|
Peptides
|
Others
|
|
RAD-KLT is a self-assembling peptide. RAD-KLT significantly enhances endothelial cell survival, proliferation, migration, and morphological tubulogenesis. RAD-KLT can be used for tissue regeneration research .
|
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- HY-P11065
-
|
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Peptides
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Others
|
|
RAD-SKP peptide is a self-assembling peptide. RAD-SKP peptide with decellularized cartilage matrix (DCM) can be used for synthesis of nanofiber hydrogel. RAD-SKP peptide can be used for cartilage repair research .
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- HY-P10453
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Peptides
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Others
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Myr5A peptide is an acylated peptide composed of apolipoprotein A1 (ApoA1) analog peptide 5A peptide coupled to the saturated fatty acid myristate. Myr5A peptide self-assembled into lipid nanostructures can be used to encapsulate anthracycline Doxorubicin (HY-15142A) and Valrubicin (HY-13772) for compound release studies in vitro .
|
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- HY-P11468
-
|
|
Bacterial
Antibiotic
|
Cardiovascular Disease
Infection
|
|
wkwkwNGwkwkw-NH2 is a self-assembling β-hairpin antimicrobial peptide. wkwkwNGwkwkw-NH2 self-assembles into nanofibers. wkwkwNGwkwkw-NH2 interacts with LPS on the surface of the bacterial membrane and then disrupts the bacterial outer membrane, inner membrane, and cytoplasmic membrane to exert its antibacterial effects. wkwkwNGwkwkw-NH2 has high antibacterial activity and low hemolytic activity. wkwkwNGwkwkw-NH2 significantly reduces the S. aureus ATCC 25923 load at the skin wound. wkwkwNGwkwkw-NH2 displays synergistic effects when combined with antibiotics. wkwkwNGwkwkw-NH2 facilitates wound healing .
|
-
- HY-P11063
-
|
|
Peptides
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Cancer
|
|
AcfffGk is a short peptide with the ability to self-assemble into helical nanofibers, forming non-covalently cross-linked hydrogels that serve as scaffolds for 3D cell culture .
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- HY-P11218
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Peptides
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Cancer
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Lipo-PtIV-R8K is a nuclear targeting peptide containing R8K. Lipo-PtIV-R8K is a lipid PtIV prodrug amphiphilic molecule that can self assemble to form nanoparticles. Lipo-PtIV-R8K can be used in the research of cancer such as breast cancer .
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- HY-P2632C
-
|
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Biochemical Assay Reagents
|
Neurological Disease
|
|
RAD16-I, free acid TFA is a derivative of RADA16 (HY-P2632), with no Ac and NH2 modifications at both ends, and it has the same function as RADA16. RAD16-I, free acid TFA is a non-directed self-assembling peptide hydrogel. Under physiological conditions, RAD16-I, free acid TFA spontaneously forms a three-dimensional nanofiber network that mimics the extracellular matrix, and possesses excellent properties such as high water content, biocompatibility and degradability. RAD16-I, free acid TFA serves as an ideal scaffold for three-dimensional cell culture. RAD16-I, free acid TFA not only maintains cell viability and induces self-organization, but also supports cell adhesion, proliferation, differentiation and insulin secretion, effectively stabilizes islet clusters and promotes directed differentiation of the cardiac lineage. RAD16-I, free acid TFA can construct a cell-friendly nano-microenvironment for research related to diseases such as myocardial infarction and diabetes .
|
-
- HY-P5423C
-
|
|
Peptides
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Others
|
|
GALA-Cys is a chemically modified GALA peptide (HY-P5423) that retains GALA functions while acquiring strong covalent conjugation capability. GALA-Cys undergoes pH-driven reversible secondary structure transition, rearranges into an amphipathic α-helix, self-oligomerizes, penetrates lipid membranes to form pores, and disrupts lipid bilayers, thereby enabling endosomal escape and cytosolic cargo delivery. GALA-Cys can be conjugated with lipid DPTE for integration into liposomes, self-assembles into a tilted monolayer on gold surfaces, and serves as a pH-responsive coating for particle surface functionalization. GALA-Cys is applicable to studies related to targeted cargo delivery .
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- HY-P11794
-
|
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Collagen
|
Others
|
|
Type IV collagen peptide is a cell-binding ligand peptide derived from type IV collagen. (The sequence is TAGSCLRKFSTM) .
|
| Cat. No. |
Product Name |
|
Classification |
-
- HY-W441011
-
|
|
|
Phospholipids
|
|
DSPE-NHS is a bioconjugation phospholipid molecule with two hydrophobic lipid tails. DSPE-NHS is a self-assembling reagent which forms lipid bilayer in aqueous solution. The NHS-ester is reactive with N-terminal of protein/peptide or other amine molecule to form a stable amide linkage. DSPE-NHS labels antibodies. DSPE-NHS can be used to prepare liposomes as agent nanocarrier .
|
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- HY-156087
-
|
|
|
Adjuvant
|
|
Cholicamideβ (GMP) is a GMP grade of Cholicamideβ. Cholicamideβ (compound 6) is a self-assembling, small molecule, cancer vaccine adjuvant. Cholicamideβ can form virus-like particles with low cytotoxicity. Cholicamideβ, upon binding to peptide antigens, enhances antigen presentation by dendritic cells and induces antigen-specific T cells. Cholicamideβ can induce apoptosis and necrosis .
|
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