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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
17 Results for "
subchronic
" in MedChemExpress (MCE) Product Catalog:
Products (17)
17 Results for "subchronic" in MCE Product Catalog:
11
11 Publications Verification
Cat. No.: HY-N0124
CAS No.: 19057-60-4
Synonyms: Collettiside III; CCRIS 4123
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Citrus × aurantium Linnaeus Rutaceae Plants Endogenous metabolite Alkaloids Monophenols Other Alkaloids Other Diseases Phenols Disease Research Fields
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Dehydrothio-p-toluidine (DHPT) is a chemical intermediate used in dyestuff production. Dehydrothio-p-toluidine shows inhalation toxicity in acute and subchronic conditions .
Cat. No.: HY-D1005A22
CAS No.: 9003-11-6
Synonyms: PEG-PPG-PEG, 14600 (Average)
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Hydroxypropylmethyl cellulose acetate succinate (Mw: 20-100k Da) is a cosolvent for preparing SDDs of low-solubility agents. Hydroxypropylmethyl cellulose acetate succinate (Mw: 20-100k Da) exhibits no acute/subchronic/chronic toxicity in rats, with oral activity and LD50 >2.5 g/kg .
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VA012 (compound 11) is a positive allosteric modulator (PAM) of the serotonin 5-HT2C receptor. VA012 reduces food intake and body weight gain without causing CNS-related malaise during subchronic administration. VA012 can be utilized in obesity research .
Cat. No.: HY-N0124R
CAS No.: 19057-60-4
Synonyms: Collettiside III (Standard); CCRIS 4123 (Standard)
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Cat. No.: HY-P10759
CAS No.: 372491-73-1
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Cat. No.: HY-P10405A
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Cat. No.: HY-118184
CAS No.: 1195786-61-8
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AF3485 is a human mPGES-1 inhibitor that exhibits antitumor activity in vitro and in vivo. AF3485 inhibits tumor-associated angiogenesis by reducing PGE2 production, inhibiting EGFR signaling, and decreasing VEGF and FGF-2 expression. AF3485 reduced tumor growth in mice bearing human A431 xenograft tumors by subchronic administration.
Cat. No.: HY-P10405
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Cat. No.: HY-111258
CAS No.: 869499-38-7
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GSK345931A is an EP1 receptor antagonist. GSK345931A shows measurable CNS penetration in the mouse and rat and potent analgesic efficacy in acute and sub-chronic models of inflammatory pain .
Cat. No.: HY-119034
CAS No.: 111542-07-5
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AD-20 is an o-methoxyphenylacetyl dehydroalanine derivative. AD-20 can not only reduce the acute and subchronic toxicity of Doxorubicin (HY-15142A), but also enhance its anti-tumor effect .
Cat. No.: HY-120783
CAS No.: 1531592-40-1
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Lu AF58801 is a potent, orally available, brain-penetrant positive allosteric modulator of α7 nicotinic acetylcholine receptors with efficacy in a novel object recognition task in mice. Lu AF58801 was shown to selectively enhance the activity of α7 nicotinic acetylcholine receptors. Lu AF58801 was able to improve cognitive function in mice treated with subchronic fluchlorothiazol (PCP) .
Cat. No.: HY-N5159
CAS No.: 197960-94-4
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Cat. No.: HY-106154
CAS No.: 274912-87-7
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DTS-201 (CPI-0004) is a peptidic prodrug of Doxorubicin (HY-15142A). DTS-201, comprising the tetrapeptide portion, is cleaved by endopeptidases in the tumor environment to produce metabolites that subsequently enter the cell and are converted to active Doxorubicin. DTS-201 shows antitumoral efficacy in tumor xenograft models of prostate, breast, and lung cancer .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
