186 Results for "

tobacco

" in MedChemExpress (MCE) Product Catalog:
Products (186)

186 Results for "tobacco" in MCE Product Catalog:

  • Targets Recommended:
7
7 Publications Verification
Cat. No.: HY-N7434
CAS No.: 55-18-5
Synonyms: Diethylnitrosamine; DEN; DENA
N-Nitrosodiethylamine (Diethylnitrosamine) is a potent hepatocarcinogenic dialkylnitrosoamine. N-Nitrosodiethylamine is mainly present in tobacco smoke, water, cheddar cheese, cured, fried meals and many alcoholic beverages. N-Nitrosodiethylamine is responsible for the changes in the nuclear enzymes associated with DNA repair/replication. N-Nitrosodiethylamine results in various tumors in all animal species. The main target organs are the nasal cavity, trachea, lung, esophagus and liver.
loading...
    loading...
4
4 Cited Publications
Cat. No.: HY-100958
CAS No.: 1952-15-4
Purity:  99.96%
Synonyms: 4-DAMP methiodide
4-DAMP (4-DAMP methiodide) is a potent and selective antagonist of M3 receptors and also has a high affinity for the closely-related M5 receptors. 4-DAMP combined with 5-Fluorouracil (5-Fu) (HY-90006) could significantly reduce the cell viability and enhance apoptosis in MKN45 and BGC823 gastric cancer cells. 4-DAMP inhibits lipopolysaccharide (LPS)- and tobacco-induced pulmonary inflammation and reduces mucin 5AC (MUC5AC), oligomeric mucus/gel-forming secretion .
loading...
    loading...
3
3 Cited Publications
Cat. No.: HY-B1178
CAS No.: 486-56-6
Synonyms: (-)-Cotinine; (S)-Cotinine; NIH-10498
Cotinine ((-)-Cotinine) is an orally active alkaloid found in tobacco and is the primary metabolite of nicotine. Cotinine is metabolized by CYP2A13 into trans-3'-hydroxycotinine. Cotinine is used as a biomarker to measure exposure to tobacco smoke components. Cotinine has vasodepressor activity. The mixture of cotinine and nicotine (Nicotine) has antiproliferative activity against pterygium. (S)-(-)-Cotinine activates nicotinic acetylcholine receptors (nAChR) in a calcium-dependent manner, leading to the release of dopamine (Dopamine, HY-B0451). Cotinine ((-)-Cotinine) is used in research related to cardiovascular and inflammatory diseases .
loading...
    loading...
2
2 Cited Publications
Cat. No.: HY-126047A
CAS No.: 2743-90-0
Purity:  98.75%
Research Areas:  

Inflammation/Immunology

(R,S)-Anatabine is a a minor tobacco alkaloid found in the Solanaceae family of plants that can be used as a specific marker for the detection of tobacco use .
loading...
    loading...
2
2 Cited Publications
Cat. No.: HY-N0576
CAS No.: 13190-97-1
Solanesol is an orally active aliphatic terpene alcohol. Solanesol is mainly found in tobacco and other Solanaceae plants. Solanesol induces HO-1 and Hsp70 expression, activates p38 and Akt signaling pathways, and inhibits Apoptosis (reduces caspase-3 and PARP cleavage). Solanesol has antioxidant, anti-inflammatory, and neuroprotective activities. Solanesol can be used in the research of Huntington's disease, alcoholic liver disease, chronic inflammatory pain, anxiety, Alzheimer's disease, and bipolar disorder .
loading...
    loading...
1
1 Cited Publications
Cat. No.: HY-Y0507
CAS No.: 302-84-1
DL-Serine, a fundamental metabolite, is a mixture of D-Serine and L-Serine. DL-Serine has antiviral activity against the multiplication of tobacco mosaic virus (TMV) .
loading...
    loading...
1
1 Cited Publications
Cat. No.: HY-W011151
CAS No.: 6025-53-2
trans-Zeatinriboside is a zeatin-type cytokinin and plant growth regulator. trans-Zeatinriboside is produced by the terrestrial filamentous cyanobacterium Nostoc sp. HK-01 and Agrobacterium tumefaciens (including Ti plasmid-dependent and Ti plasmid-independent strains). trans-Zeatinriboside is detectable as a cytokinin component in growing crown galls, and accumulates in large amounts in CHRK1-silenced transgenic tobacco accompanied by pleiotropic developmental abnormalities. trans-Zeatinriboside can be used in studies related to crown galls .
loading...
    loading...
1
1 Cited Publications
Cat. No.: HY-103673
CAS No.: 2139356-35-5
Purity:  99.52%
Target:  

Adenosine Deaminase

Research Areas:  

Neurological Disease

AMPD2 inhibitor 1 is an adenosine monophosphate deaminase 2 (AMPD2) inhibitor, used in the research of sugar craving, salt craving, umami craving, and addictions including agent, tobacco, nicotine and alcohol addictions.
loading...
    loading...
1
1 Cited Publications
Cat. No.: HY-19918A
Anatabine dicitrate is a tobacco alkaloid that can cross the blood-brain barrier. Anatabine dicitrate is a potent α4β2 nAChR agonist. Anatabine dicitrate inhibits NF-κB activation lower amyloid-β (Aβ) production by preventing the β-cleavage of amyloid precursor protein (APP). Anatabine dicitrate has anti-inflammatory effects and has the potential for neurodegenerative disorders treatment .
loading...
    loading...
1
1 Cited Publications
Cat. No.: HY-W016393
CAS No.: 2305-13-7
Dihydroconiferyl alcohol is a cell division factor. Dihydroconiferyl alcohol can be isolated from the American sycamore (Acer pseudoplatanus L.). Dihydroconiferyl alcohol inhibits the degradation of Indole-3-acetic acid (HY-18569). Dihydroconiferyl alcohol can stimulate the growth of soybean and tobacco callus tissue and synergistically enhance Indole-3-acetic acid-induced hypocotyl elongation in cucumber. Dihydroconiferyl alcohol can be used in the research of plant growth regulation .
loading...
    loading...
1
1 Cited Publications
Cat. No.: HY-P5712
CAS No.: 113-73-5
Synonyms: Gramicidin soviet
Research Areas:  

Infection

Gramicidin S (Gramicidin soviet) is a cationic cyclic peptide antibiotic that selectively targets bacterial cell membranes and has anticancer activity. Gramicidin S also exerts antibacterial activity by destroying membrane integrity and interfering with membrane protein function. Gramicidin S inserts into the phospholipid bilayer through hydrophobic amino acid residues, specifically binds to negatively charged membrane lipids and disrupts membrane structure, thereby inhibiting cell division and cell wall synthesis, and ultimately causing bacterial death. Gramicidin S also inhibits ion channels, with IC50s of 41 μM, 24 μM, and 3 μM for Na +/K +-ATPase, tobacco leaf plasma membrane Mg 2+/K +-ATPase, and rat heart plasma membrane Ca 2+-ATPase, respectively .
loading...
    loading...
1
1 Cited Publications
Cat. No.: HY-Y0262
CAS No.: 144-62-7
Synonyms: Ethanedioic acid
Oxalic acid, 99% (Ethanedioic acid) is a dicarboxylic acid found in a wide variety of plants. Oxalic acid, 99% shows antioxidant acyivity and suppresses lipid peroxidation. Oxalic acid, 99% is a pathogenicity factor for sclerotinia sclerotiorum, and suppresses the oxidative burst of the host plant. Oxalic acid, 99% exerts acaricidal activity. Oxalic acid can be used for the researches of sclerotinia disease, varroatosis and inflammatory diseases .
loading...
    loading...
1
1 Cited Publications
Cat. No.: HY-Y0262A
CAS No.: 6009-70-7
Synonyms: Ethanedioic acid diammonium monohydrate
Oxalic acid (Ethanedioic acid) diammonium monohydrate is a dicarboxylic acid found in a wide variety of plants.
Oxalic acid diammonium monohydrate shows antioxidant acyivity and suppresses lipid peroxidation.
Oxalic acid diammonium monohydrate is a pathogenicity factor for sclerotinia sclerotiorum, and suppresses the oxidative burst of the host plant. Oxalic acid diammonium monohydrate exerts acaricidal activity. Oxalic acid can be used for the researches of sclerotinia disease varroatosis and inflammatory diseases .
loading...
    loading...
Cat. No.: HY-Y0189
CAS No.: 119-36-8
Synonyms: Salicylic acid methyl ester
Methyl Salicylate (Wintergreen oil) is a topical analgesic and anti-inflammatory agent. Also used as a pesticide, a denaturant, a fragrance ingredient, and a flavoring agent in food and tobacco products . A systemic acquired resistance (SAR) signal in tobacco . A topical nonsteroidal anti-inflammatory agent (NSAID). Methyl salicylate lactoside is a COX inhibitor .
loading...
    loading...
Cat. No.: HY-W041301
CAS No.: 15356-74-8
(±)-Dihydroactinidiolide is the dextrorotatory form of Dihydroactinidiolide (HY-107805). (±)-Dihydroactinidiolide has a strong, pleasant musky, tea-like and tobacco-like aroma and is mainly found in black tea, tobacco and fruits. (±)-Dihydroactinidiolide has antioxidant activity and can be derived from β-carotene.or light adaptation in Arabidopsis .
loading...
    loading...
Cat. No.: HY-121999
CAS No.: 17990-16-8
Purity:  99.54%
Synonyms: (Z)-Abienol
(+)-cis-Abienol (Compound Z-abienol), a diterpenoid, can be isolated from leaves of tobacco. (+)-cis-Abienol inhibits hyphal growth of P. nicotianae .
loading...
    loading...
Cat. No.: HY-B1673
CAS No.: 64044-51-5
D-Lactose monohydrate is a sugar. D-Lactose monohydrate can be utilized by most bacteria. D-Lactose monohydrate promotes the growth of tobacco B6S3 tumor tissue. D-Lactose monohydrate is used in the research of the growth mechanism of plant tumor tissues and the sugar utilization of bacteria .
loading...
    loading...
Cat. No.: HY-W001909
CAS No.: 532-12-7
Myosmine, a specific tobacco alkaloid in nuts and nut products, has low affinity for a4b2 nicotinic acetylcholinergic receptors (nAChR) with a Ki of 3300 nM .
loading...
    loading...
Cat. No.: HY-34516
CAS No.: 16682-12-5
Synonyms: (R)-Ornithine hydrochloride
D-Ornithine ((R)-Ornithine) hydrochloride is a constituent of bacterial cell wall. D-Ornithine hydrochloride promotes the production of L-arginine (HY-N0455). D-Ornithine hydrochloride enhances the expression of pyrrolysine-containing proteins .
loading...
    loading...
Cat. No.: HY-Y0507S
CAS No.: 70094-78-9
DL-Serine-2,3,3-d3 is the deuterium labeled DL-Serine. DL-Serine, a fundamental metabolite, is a mixture of D-Serine and L-Serine. DL-Serine has antiviral activity against the multiplication of tobacco mosaic virus (TMV) .
loading...
    loading...