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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
33 Results for "
urokinase-type plasminogen activator (uPA)
" in MedChemExpress (MCE) Product Catalog:
Products (33)
33 Results for "urokinase-type plasminogen activator (uPA)" in MCE Product Catalog:
3
3 Cited Publications
Target:
Research Areas:
UK122 is a potent and selective urokinase-type plasminogen activator (uPA) inhibitor with an IC50 of 0.2 μM. UK122 shows no or little inhibition of tissue-type PA (tPA), plasmin, thrombin, and trypsin (all IC50>100 μM). UK122, 4-oxazolidinone analogue, is an anticancer agent and inhibits cancer cell migration and invasion .
3
3 Cited Publications
Cat. No.: HY-111056A
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UK122 hydrochloride is a potent and selective urokinase-type plasminogen activator (uPA) inhibitor with an IC50 of 0.2 μM. UK122 hydrochloride shows no or little inhibition of tissue-type PA (tPA), plasmin, thrombin, and trypsin (all IC50s > 100 μM). UK122 hydrochloride, a 4-oxazolidinone analogue, is an anticancer agent and inhibits cancer cell migration and invasion .
2
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Upamostat (WX-671), a prodrug of WX-UK1, is an orally active serine protease inhibitor. Upamostat inhibits the urokinase-type plasminogen activator (uPA) system, blocking the plasminogen activation process mediated by it, thereby suppressing the invasion, migration and metastasis of tumor cells. Upamostat can be used in the research of metastatic breast cancer and locally advanced pancreatic cancer .
2
2 Cited Publications
Cat. No.: HY-W018723
CAS No.: 2498-50-2
Synonyms: p-Aminobenzamidine dihydrochloride
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4-Aminobenzamidine (p-Aminobenzamidine) dihydrochloride is a strong trypsin inhibitor. 4-Aminobenzamidine dihydrochloride acts as an orally active urokinase type plasminogen activator (uPA) inhibitor (Ki=82 μM). 4-Aminobenzamidine dihydrochloride can be used for cardiovascular diseases and anti-tumor study .
2
2 Cited Publications
Cat. No.: HY-P71050
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: PLAU; plasminogen activator, Urinary; plasminogen activator, urokinase; PLAU Protein; UPA; BDPLT5; urokinase-type plasminogen activator; U-PA; URK; ATF; U-plasminogen activator; QPD
Species:
Human
Source:
HEK293
1
1 Cited Publications
Cat. No.: HY-P78017
Purity: ≥ 95%, as determined by reducing SDS-PAGE or Bis-Tris PAGE.
Synonyms: PLAU; plasminogen activator, Urinary; plasminogen activator, urokinase; PLAU Protein; UPA; BDPLT5; urokinase-type plasminogen activator; U-PA; URK; ATF; U-plasminogen activator; QPD
Species:
Mouse
Source:
HEK293
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UK-371804 is a urokinase-type plasminogen activator (uPA) inhibitor with a Ki of 10 nM.
Cat. No.: HY-P11446
CAS No.: 254729-66-3
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Synonyms: WX-UK1; UKI-1C
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UKI-1 (WX-UK1) is a potent urokinase-type plasminogen activator (uPA) inhibitor with a Ki of 0.41 μM. UKI-1 is also a low molecular weight serine protease inhibitor. UKI-1 is a potent antimetastatic agent and inhibits the invasive capacity of carcinoma cells .
Cat. No.: HY-P4254
CAS No.: 201735-59-3
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Cat. No.: HY-P10877
CAS No.: 1393680-45-9
Cat. No.: HY-P11023
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Cat. No.: HY-W013964
CAS No.: 39959-59-6
Synonyms: (4-Iodophenyl)methanamine
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4-Iodobenzylamine ((4-Iodophenyl)methanamine) is a probe that can detect the binding patterns of serine proteases that are like trypsin, as well as urokinase-type plasminogen activator (uPA). 4-Iodobenzylamine is stable in aqueous solution .
Cat. No.: HY-P11446A
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Cat. No.: HY-101214A
CAS No.: 256476-36-5
UK-371804 hydrochloride (compound 24) is a urokinase-type plasminogen activator (uPA) inhibitor with a Ki of 10 nM .
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Cat. No.: HY-137495A
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Cat. No.: HY-W104868
CAS No.: 59528-27-7
Research Areas:
4-Iodobenzylamine hydrochloride ((4-Iodophenyl)methanamine hydrochloride) is a probe that can detect the binding patterns of serine proteases that are like trypsin, as well as urokinase-type plasminogen activator (uPA) .
Cat. No.: HY-135715
CAS No.: 1186653-73-5
(E)-UK122 TFA is the isomer of UK122 TFA. UK122 is a potent and selective urokinase-type plasminogen activator (uPA) inhibitor with an IC50 of 0.2 μM .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
