2498-50-2
2498-50-2
Chemical Structure
4-Aminobenzamidine dihydrochloride
Synonym(s): p-Aminobenzamidine dihydrochloride
- CAS No.: 2498-50-2
- Formula:C7H11Cl2N3
- Molecular Weight:208.09
IUPAC Name: 4-aminobenzimidamide dihydrochloride
InChIKey: GHEHNICLPWTXJC-UHFFFAOYSA-N
SMILES: N=C(N)C1=CC=C(N)C=C1.[H]Cl.[H]Cl
Biological Activity: 4-Aminobenzamidine (p-Aminobenzamidine) dihydrochloride is a strong trypsin inhibitor. 4-Aminobenzamidine dihydrochloride acts as an orally active urokinase type plasminogen activator (uPA) inhibitor (Ki=82 μM). 4-Aminobenzamidine dihydrochloride can be used for cardiovascular diseases and anti-tumor study[1][2][3][4].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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4-Aminobenzamidine dihydrochloride | 99.97% | 4-Aminobenzamidine (p-Aminobenzamidine) dihydrochloride is a strong trypsin inhibitor. 4-Aminobenzamidine dihydrochloride acts as an orally active urokinase type plasminogen activator (uPA) inhibitor (Ki=82 μM). 4-Aminobenzamidine dihydrochloride can be used for cardiovascular diseases and anti-tumor study. | ||||||||||||||||||||
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References
- [1]. Nguyen AL, et al. The development and application of a new affinity partitioning system for enzyme isolation and purification. Enzyme Microb Technol. 1990 Sep;12(9):663-8. [Content Brief]
- [2]. Billström A, et al. The urokinase inhibitor p-aminobenzamidine inhibits growth of a human prostate tumor in SCID mice. Int J Cancer. 1995 May 16;61(4):542-7. [Content Brief]
- [3]. Okumura N, et al. Cell surface-bound plasminogen regulates hepatocyte proliferation through a uPA-dependent mechanism. Biosci Biotechnol Biochem. 2007 Jun;71(6):1542-9. [Content Brief]
- [4]. Dutra JBR, et al. p-Aminobenzamidine attenuates cardiovascular dysfunctions in spontaneously hypertensive rats. Life Sci. 2022 Sep 1;304:120693. [Content Brief]
