2. Metabolic Enzyme/Protease
  3. Epoxide Hydrolase
  4. sEH inhibitor-11

sEH inhibitor-11 (compound 35) is a sEH inhibitor with an IC50 value of 0.3 μM. sEH inhibitor-11 can be used for the research of inflammation.

For research use only. We do not sell to patients.

sEH inhibitor-11 Chemical Structure

sEH inhibitor-11 Chemical Structure

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sEH inhibitor-11 Related Antibodies

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Description

sEH inhibitor-11 (compound 35) is a sEH inhibitor with an IC50 value of 0.3 μM. sEH inhibitor-11 can be used for the research of inflammation[1].

IC50 & Target

IC50: 0.3 μM (sEH)[1]
In Vitro

sEH inhibitor-11 (0-10 μM; 10 min) inhibits sEH activity with an IC50 value of 0.3 μM[1].
sEH inhibitor-11 (0-10 μM) inhibits 5-lipoxygenase-activating protein (FLAP)-mediated cellular leukotriene (LT) formation with an IC50 value of ＞10 μM[1].
sEH inhibitor-11 (15 min) remains the activity of 5-lipoxygenase (5-LO) product formation in neutrophils with 93.5% and 62.1% at doses of 1 and 10 μM, respectively[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

sEH inhibitor-11 Related Antibodies
Molecular Weight

415.94

Formula

C21H22ClN3O2S
SMILES

O=C(C1=CC(N=C(SCC2=CC=CC(Cl)=C2)N3)=C(C=C1)C3=O)NCC(C)(C)C
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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sEH inhibitor-11 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

sEH inhibitor-11sEH inhibitor11sEH inhibitor 11Epoxide Hydrolasequinazolinone-7-carboxylic acidderivativeFLAP5-LOLTneutrophilsInhibitorinhibitorinhibit

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sEH inhibitor-11
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HY-151617
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