sEH inhibitor-11
sEH inhibitor-11 (compound 35) is a sEH inhibitor with an IC50 value of 0.3 μM. sEH inhibitor-11 can be used for the research of inflammation.
For research use only. We do not sell to patients.
- Formula: C21H22ClN3O2S
- Molecular Weight:415.94
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
IC50: 0.3 μM (sEH)[1]
sEH inhibitor-11 (0-10 μM; 10 min) inhibits sEH activity with an IC50 value of 0.3 μM[1]. sEH inhibitor-11 (0-10 μM) inhibits 5-lipoxygenase-activating protein (FLAP)-mediated cellular leukotriene (LT) formation with an IC50 value of ＞10 μM[1]. sEH inhibitor-11 (15 min) remains the activity of 5-lipoxygenase (5-LO) product formation in neutrophils with 93.5% and 62.1% at doses of 1 and 10 μM, respectively[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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Molecular Weight 415.94
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Formula C21H22ClN3O2S
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SMILES
O=C(C1=CC(N=C(SCC2=CC=CC(Cl)=C2)N3)=C(C=C1)C3=O)NCC(C)(C)C
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
sEH inhibitor-11 Related Classifications
HY-151617 Related Classifications
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