SM 10888
SM 10888 is a selective and orally active cholinesterase (ChE) inhibitor. SM 10888 can increase brain acetylcholine release. SM 10888 can be used for the research of neurological disease, such as Alzheimer's disease.
For research use only. We do not sell to patients.
- CAS No.: 129297-21-8
- Formula: C20H21FN2O7
- Molecular Weight:420.39
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
Chemical Information
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CAS No. 129297-21-8
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Molecular Weight 420.39
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Formula C20H21FN2O7
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SMILES
NC1=C(C(F)=CC=C2)C2=NC3=C1CC4CC3C4.OC(C(O)=O)(CC(O)=O)CC(O)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. Xu M, et al. Determination of basal acetylcholine release in vivo by rat brain dialysis with a U-shaped cannula: effect of SM-10888, a putative therapeutic drug for Alzheimer's disease. Neurosci Lett. 1991 Feb 25;123(2):179-82. [Content Brief]
[2]. Okazaki Y, et al. Effect of a novel CNS-selective cholinesterase inhibitor, SM-10888, on habituation and passive avoidance responses in mice. Jpn J Pharmacol. 1990 Jun;53(2):211-20. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)