Spiroxasone
Spiroxasone is an orallyactive thioacetyl-containing steroid. Spiroxasone can prevent fatal renal damage and nephrocalcinosis associated with acute mercuric chloride intoxication. Spiroxasone can be used for the research of acute HgCl2 poisoning.
For research use only. We do not sell to patients.
- CAS No.: 6673-97-8
- Formula: C24H34O3S
- Molecular Weight:402.59
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Animal Model:ARS/Sprague-Dawley with acute mercuric chloride poisoning (female, 90-110 g)[1]
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Dosage:10 mg
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Administration:p.o.; 1 hour before HgCl₂ administration
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Result:Achieved a nephrocalcinosis score of 0 (no lesion) and yielded 0% mortality.
Chemical Information
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CAS No. 6673-97-8
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Molecular Weight 402.59
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Formula C24H34O3S
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SMILES
CC(S[C@H]1[C@@]2([H])[C@@]3([H])[C@@]([C@]4(CCCO4)CC3)(CC[C@]2([H])[C@@]5(C(C1)=CC(CC5)=O)C)C)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)