Sprengerinin C
Sprengerinin is a potential angiogenesis inhibitor. Sprengerinin exerts anti-tumorigenic effects in vitro.
For research use only. We do not sell to patients.
- CAS No.: 88861-91-0
- Formula: C44H70O16
- Molecular Weight:855.02
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
IC50: angiogenesis[1]
|
Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| BXPC-3 | GI50 |
0.47 μg/mL
Compound: 6
|
Growth inhibition of humanBxPC3 cells after 48 hrs
Growth inhibition of humanBxPC3 cells after 48 hrs
|
[PMID: 15921418] |
| DU-145 | GI50 |
>10 μg/mL
Compound: 6
|
Growth inhibition of human DU145 cells after 48 hrs
Growth inhibition of human DU145 cells after 48 hrs
|
[PMID: 15921418] |
| KM-20L2 | GI50 |
0.5 μg/mL
Compound: 6
|
Growth inhibition of human KM20L2 cells after 48 hrs
Growth inhibition of human KM20L2 cells after 48 hrs
|
[PMID: 15921418] |
| MCF7 | GI50 |
0.22 μg/mL
Compound: 6
|
Growth inhibition of human MCF7 cells after 48 hrs
Growth inhibition of human MCF7 cells after 48 hrs
|
[PMID: 15921418] |
| NCI-H460 | GI50 |
1.7 μg/mL
Compound: 6
|
Growth inhibition of human NCI-H460 cells after 48 hrs
Growth inhibition of human NCI-H460 cells after 48 hrs
|
[PMID: 15921418] |
| P388 | ED50 |
>10 μg/mL
Compound: 6
|
Growth inhibition of mouse P388 cells after 48 hrs
Growth inhibition of mouse P388 cells after 48 hrs
|
[PMID: 15921418] |
| SF-268 | GI50 |
1.6 μg/mL
Compound: 6
|
Growth inhibition of human SF268 cells after 48 hrs
Growth inhibition of human SF268 cells after 48 hrs
|
[PMID: 15921418] |
Chemical Information
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CAS No. 88861-91-0
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Molecular Weight 855.02
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Formula C44H70O16
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SMILES
C[C@@]12[C@]3([H])[C@](O[C@]4(CC[C@H](CO4)C)[C@H]3C)([H])C[C@@]1([H])[C@@]5([H])[C@]([C@@]6(C(C[C@H](CC6)O[C@H]7[C@@H]([C@H]([C@@H]([C@H](O7)CO)O[C@H]8[C@@H]([C@H]([C@@H](CO8)O)O)O)O)O[C@H]9[C@@H]([C@@H]([C@H]([C@@H](O9)C)O)O)O)=CC5)C)([H])CC2
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Structure Classification
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Initial Source
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)