Sul-121 hydrochloride

Sul-121 hydrochloride is a novel compound with anti-oxidative capacity that effectively inhibits airway inflammation and hyperresponsiveness (AHR) in experimental models of chronic obstructive pulmonary disease (COPD). Sul-121 hydrochloride prevents lipopolysaccharide-induced airway neutrophilia and AHR in a dose-dependent manner. Sul-121 hydrochloride also demonstrates the ability to reduce oxidative stress markers in human airway smooth muscle cells. Sul-121 hydrochloride inhibits nuclear translocation of the NF-κB subunit, p65, thereby diminishing pro-inflammatory cytokine release.

For research use only. We do not sell to patients.

  • CAS No.: 1541170-25-5
  • Formula: C18H27ClN2O3
  • Molecular Weight:354.87
  • Storage:

    Please store the product under the recommended conditions in the Certificate of Analysis.

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