1. Metabolic Enzyme/Protease
  2. Tyrosinase
  3. Swertiajaponin

Swertiajaponin 

Cat. No.: HY-N2204
Handling Instructions

Swertiajaponin is a tyrosinase inhibitor, forms multiple hydrogen bonds and hydrophobic interactions with the binding pocket of tyrosinase, with an IC50 of 43.47 μM. Swertiajaponin also inhibits oxidative stress-mediated MAPK/MITF signaling, leading to decrease in tyrosinase protein level. Swertiajaponin suppresses melanin accumulation and exhibits strong anti-oxidative activity.

For research use only. We do not sell to patients.

Swertiajaponin Chemical Structure

Swertiajaponin Chemical Structure

CAS No. : 6980-25-2

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Description

Swertiajaponin is a tyrosinase inhibitor, forms multiple hydrogen bonds and hydrophobic interactions with the binding pocket of tyrosinase, with an IC50 of 43.47 μM. Swertiajaponin also inhibits oxidative stress-mediated MAPK/MITF signaling, leading to decrease in tyrosinase protein level. Swertiajaponin suppresses melanin accumulation and exhibits strong anti-oxidative activity[1].

IC50 & Target

IC50: 43.47 μM (tyrosinase)[1]

Molecular Weight

462.40

Formula

C₂₂H₂₂O₁₁

CAS No.

6980-25-2

SMILES

O=C1C=C(C2=CC=C(O)C(O)=C2)OC3=CC(OC)=C([[email protected]]4[[email protected]@H]([[email protected]]([[email protected]@H]([[email protected]@H](CO)O4)O)O)O)C(O)=C13

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Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

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