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Cat. No.: HY-146404

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T761-0184

T761-0184 is a potent α7 nicotinic receptor (nAChR) antagonist.

For research use only. We do not sell to patients.

CAS No.: 1340907-57-4
Formula: C₁₆H₂₀FN₃O
Molecular Weight:289.35

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (266 KB)

T761-0184 Chemical Structure

CAS No.: 1340907-57-4

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity

Description

T761-0184 is a potent α7 nicotinic receptor (nAChR) antagonist^[1].

Chemical Information

CAS No. 1340907-57-4
Molecular Weight 289.35
Formula C₁₆H₂₀FN₃O
SMILES

FC1=CC=C(C=C1)CN2CCC3(NC(C4CC4)=NO3)CC2
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (266 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Zhang H, et al. Design, synthesis and biological activities of piperidine-spirooxadiazole derivatives as α7 nicotinic receptor antagonists[J]. European Journal of Medicinal Chemistry, 2020, 207: 112774.

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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