2. Metabolic Enzyme/Protease
  3. TrxR
  4. TrxR1-IN-1

TrxR1-IN-1 (Compound 5j) is a TrxR1 inhibitor (IC50: 8.8 μM). TrxR1-IN-1 has anticancer activity, with IC50s of MCF-7 (1.5 μM), HeLa (1.7 μM), BGC-823 (2.4 μM), SW-480 (2.8 μM), A549 (2.1 μM). TrxR1-IN-1 has antioxidant activity, and scavenges DPPH radical.

For research use only. We do not sell to patients.

TrxR1-IN-1 Chemical Structure

TrxR1-IN-1 Chemical Structure

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TrxR1-IN-1 Related Antibodies

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Description

TrxR1-IN-1 (Compound 5j) is a TrxR1 inhibitor (IC50: 8.8 μM). TrxR1-IN-1 has anticancer activity, with IC50s of MCF-7 (1.5 μM), HeLa (1.7 μM), BGC-823 (2.4 μM), SW-480 (2.8 μM), A549 (2.1 μM). TrxR1-IN-1 has antioxidant activity, and scavenges DPPH radical[1].

IC50 & Target

8.8 μM (TrxR1)[1]
Molecular Weight

465.36

Formula

C23H18N2O4Se
SMILES

O=C1N(C2=CC=C(CNC(C3=C(C=CC=C3)OC(C)=O)=O)C=C2)[Se]C4=CC=CC=C41
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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TrxR1-IN-1 Related Classifications

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

TrxR1-IN-1TrxRThioredoxin ReductaseantioxidantDPPH radicalanticancerMCF-7HeLaBGC-823SW-480A549Inhibitorinhibitorinhibit

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