Cudraxanthone D
Cudraxanthone D is a Xanthones product that can be isolated from the roots of Cudrania tricuspidata.
For research use only. We do not sell to patients.
- CAS No.: 96552-41-9
- Formula: C24H26O6
- Molecular Weight:410.46
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
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Help & FAQs
Biological Activity
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| BTI-TN-5B1-4 | IC50 |
57.6 μM
Compound: 3
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Inhibition of human ACAT1 expressed in Hi5 cells
Inhibition of human ACAT1 expressed in Hi5 cells
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[PMID: 16919944] |
| BTI-TN-5B1-4 | IC50 |
75.2 μM
Compound: 3
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Inhibition of human ACAT2 expressed in Hi5 cells
Inhibition of human ACAT2 expressed in Hi5 cells
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[PMID: 16919944] |
| RAW264.7 | IC50 |
16.1 μM
Compound: 23
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Antiinflammatory activity in mouse RAW264.7 cells assessed as inhibition of LPS-stimulated nitric oxide production after 24 hrs by Griess method
Antiinflammatory activity in mouse RAW264.7 cells assessed as inhibition of LPS-stimulated nitric oxide production after 24 hrs by Griess method
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[PMID: 26073007] |
| SH-SY5Y | EC50 |
>50 μM
Compound: Cudraxanthone D
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Neuroprotective activity in human SH-SY5Y cells assessed as reduction in 1-methyl-4-phenylpyridinium ion-induced cell death after 48 hrs by MTT assay
Neuroprotective activity in human SH-SY5Y cells assessed as reduction in 1-methyl-4-phenylpyridinium ion-induced cell death after 48 hrs by MTT assay
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[PMID: 27420919] |
| SH-SY5Y | EC50 |
4.8 μM
Compound: Cudraxanthone D
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Neuroprotective activity in human SH-SY5Y cells assessed as reduction in oxygen glucose deprivation-induced cell death incubated for 16 hrs under hypoxic condition followed by incubation for 24 hrs under normoxic condition by MTT assay
Neuroprotective activity in human SH-SY5Y cells assessed as reduction in oxygen glucose deprivation-induced cell death incubated for 16 hrs under hypoxic condition followed by incubation for 24 hrs under normoxic condition by MTT assay
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[PMID: 27420919] |
Chemical Information
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CAS No. 96552-41-9
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Molecular Weight 410.46
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Formula C24H26O6
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SMILES
O=C1C2=C(OC3=C1C(O)=CC(OC)=C3C(C)(C)C=C)C=C(O)C(O)=C2C/C=C(C)\C
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Initial Source
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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