Z2768276635
Z2768276635 is an Arabidopsis thaliana acetohydroxyacid synthase (AHAS) inhibitor with a Ki of 0.12 μM, and a Kd of 0.565 μM.Z2768276635 forms a covalent bond with the Ser653 residue of AtAHAS to inhibit catalytic activity.Z2768276635 can be used for the research of weed herbicide resistance.
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- CAS No.: 2920564-49-2
- 화학식: C20H21FN2O5S
- 분자량:420.45
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보관:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- 순도&문서
- References
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Help & FAQs
Biological Activity
Z2768276635 (1 h) potently inhibits Arabidopsis thaliana AHAS (AHAS) with a Ki of 0.12 μM[1].
Z2768276635 binds strongly to wild-type Arabidopsis thaliana AHAS (WT-AtAHAS) with a binding constant of 104.396, and binding affinity is significantly reduced for Ser653-to-Thr mutant AtAHASS653T (MutS653T-AtAHAS), demonstrating Ser653 is critical for high-affinity binding[1].
Z2768276635 binds to wild-type Arabidopsis thaliana AHAS (WT-AtAHAS) with a dissociation constant of 0.565 μM, and binding affinity is weaker for Ser653-to-Thr mutant AtAHASS653T (MutS653T-AtAHAS), confirming Ser653 is critical for high-affinity binding[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 2920564-49-2
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분자량 420.45
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화학식 C20H21FN2O5S
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SMILES
O=S(C1=CC=CC(C(NCC2=CC=CC(C(NCC3OCCC3)=O)=C2)=O)=C1)(F)=O
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선적
Room temperature in continental US; may vary elsewhere.
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보관
Please store the product under the recommended conditions in the Certificate of Analysis.
순도&문서
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Z2768276635 Related Classifications
HY-184215 Related Classifications
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