ZW-2038
ZW-2038 is a potent and selective antiviral compound against vaccinia virus (VACV), monkeypox virus (MPXV), and cowpox virus (CPXV). ZW-2038 suppresses VACV DNA replication and downstream post-replicative gene expression, albeit without inhibiting MPXV resolvase (Mpr). ZW-2038 demonstrates potent antiviral activity in complex human and animal tissue models. ZW-2038 can be used for orthopoxviruses infection research.
For research use only. We do not sell to patients.
- Formula: C21H17F3N2O3
- Molecular Weight:402.37
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| HFF | CC50 |
50 μM
Compound: 15
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Cytotoxicity against human HFF cells assessed as reduction in cell viability
Cytotoxicity against human HFF cells assessed as reduction in cell viability
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[PMID: 37827528] |
Chemical Information
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Molecular Weight 402.37
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Formula C21H17F3N2O3
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SMILES
O=C(C1=CN(C=C(C1=O)O)CC2=CC=C(C=C2)F)NCCC3=C(C=C(C=C3)F)F
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
ZW-2038 Related Classifications
HY-180883 Related Classifications
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