β-Endorphin (1-27) (human)
β-Endorphin (1-27) (human) is an opioid antagonist that binds μ-, δ-, and κ-opioid receptors with Kis of 5.31, 6.17, and 39.82 nM, respectively. β-Endorphin (1-27) (human) inhibits β-Endorphin (HY-P1502)-induced and etorphine-induced analgesia.
For research use only. We do not sell to patients.
- CAS No.: 76622-84-9
- Formula: C139H217N33O40S
- Molecular Weight:3022.47
-
Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
Biological Activity
-
Chemical Information
- Purity & Documentation
- References
-
Help & FAQs
All Opioid Receptor Isoforms
More
Biological Activity
Ki: 5.31 nM (μ-opioid receptor), 6.17 nM (δ-opioid receptor), 39.82 nM (κ-opioid receptor)[1]
Chemical Information
-
CAS No. 76622-84-9
-
Molecular Weight 3022.47
-
Formula C139H217N33O40S
-
Sequence
Tyr-Gly-Gly-Phe-Met-Thr-Ser-Glu-Lys-Ser-Gln-Thr-Pro-Leu-Val-Thr-Leu-Phe-Lys-Asn-Ala-Ile-Ile-Lys-Asn-Ala-Tyr
-
Sequence Shortening
YGGFMTSEKSQTPLVTLFKNAIIKNAY
-
Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. Mansour A, et al. The cloned mu, delta and kappa receptors and their endogenous ligands: evidence for two opioid peptide recognition cores. Brain Res. 1995 Nov 27;700(1-2):89-98. [Content Brief]
[2]. Nicolas P, et al. Beta-endorphin-(1-27) is a naturally occurring antagonist to etorphine-induced analgesia. Proc Natl Acad Sci U S A. 1985 May;82(10):3178-81. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
β-Endorphin (1-27) (human) Related Classifications
HY-P5892 Related Classifications
Powered by Bioz