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Cat. No.: HY-137288

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17-Phenyl-18,19,20-trinor-PGD2

Name: 17-Phenyl-18,19,20-trinor-PGD2
Brand: MedChemExpress
SKU: HY-137288
Price: 158.00 USD
Availability: InStock
Rating: 5 (1 reviews)

(Synonyms: 17-Phenyl-PGD2)

17-Phenyl-18,19,20-trinor-PGD2 (17-Phenyl-PGD2) is an analogue of prostaglandin D2 (PGD2; HY-101988). 17-Phenyl-18,19,20-trinor-PGD2 is a potent inhibitor of platelet aggregation caused by aenosine diphosphate (ADP), with the IC₅₀ of 8.4 μM (PGD2 IC₅₀ = 18.6 nM). 17-Phenyl-18,19,20-trinor-PGD2 is a weak agonist of cyclic AMP accumulation.

For research use only. We do not sell to patients.

CAS No.: 85280-91-7
Formula: C₂₃H₃₀O₅
Molecular Weight:386.48

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (272 KB)

17-Phenyl-18,19,20-trinor-PGD2 Chemical Structure

CAS No.: 85280-91-7

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity

Description

All Prostaglandin Receptor Isoforms :

Chemical Information

CAS No. 85280-91-7
Molecular Weight 386.48
Formula C₂₃H₃₀O₅
SMILES

OC(CCC/C=C\C[C@@H]1[C@H](C(C[C@@H]1O)=O)/C=C/[C@@H](O)CCC2=CC=CC=C2)=O
Synonyms

17-Phenyl-PGD2
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Protocols

All Cell Biology

Cell Cytotoxicity Assay
Cytotoxicity assays are usually based on the assessment of cell membrane damage, which can also be indirectly detected by measuring cell viability. Detection methods include MTT assay, CKK-8 assay, LDH assay and ATP assay, etc.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (272 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. S Narumiya, et al. Different responsiveness of prostaglandin D2-sensitive systems to prostaglandin D2 and its analogues. Br J Pharmacol. 1985 Jun;85(2):367-75. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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