2. Epigenetics
  3. DNA Methyltransferase
  4. 2′,3′,5′-Triacetyl-5-azacytidine

2′,3′,5′-Triacetyl-5-azacytidine 

Cat. No.: HY-112551 Purity: 98.09%
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2′,3′,5′-Triacetyl-5-azacytidine is an orally active proagent of 5-Azacytidine. 5-Azacytidine is an inhibitor of DNA methyltransferase.

For research use only. We do not sell to patients.

2′,3′,5′-Triacetyl-5-azacytidine

2′,3′,5′-Triacetyl-5-azacytidine Chemical Structure

CAS No. : 10302-78-0

Size Price Stock Quantity
Solid + Solvent (Highly Recommended)
10 mM * 1 mL in DMSO
ready for reconstitution
 In-stock
Solution
10 mM * 1 mL in DMSO In-stock
Solid
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250 mg In-stock
1 g In-stock
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Based on 1 publication(s) in Google Scholar

2′,3′,5′-Triacetyl-5-azacytidine Related Antibodies

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Description

2′,3′,5′-Triacetyl-5-azacytidine is an orally active proagent of 5-Azacytidine. 5-Azacytidine is an inhibitor of DNA methyltransferase[1].

Molecular Weight

370.31

Formula

C14H18N4O8
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

CC(O[C@@H]1[C@H](OC(C)=O)[C@@H](COC(C)=O)O[C@H]1N2C(N=C(N)N=C2)=O)=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 100 mg/mL (270.04 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.7004 mL 13.5022 mL 27.0044 mL
5 mM 0.5401 mL 2.7004 mL 5.4009 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

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(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 2.7004 mL 13.5022 mL 27.0044 mL 67.5110 mL
5 mM 0.5401 mL 2.7004 mL 5.4009 mL 13.5022 mL
10 mM 0.2700 mL 1.3502 mL 2.7004 mL 6.7511 mL
15 mM 0.1800 mL 0.9001 mL 1.8003 mL 4.5007 mL
20 mM 0.1350 mL 0.6751 mL 1.3502 mL 3.3756 mL
25 mM 0.1080 mL 0.5401 mL 1.0802 mL 2.7004 mL
30 mM 0.0900 mL 0.4501 mL 0.9001 mL 2.2504 mL
40 mM 0.0675 mL 0.3376 mL 0.6751 mL 1.6878 mL
50 mM 0.0540 mL 0.2700 mL 0.5401 mL 1.3502 mL
60 mM 0.0450 mL 0.2250 mL 0.4501 mL 1.1252 mL
80 mM 0.0338 mL 0.1688 mL 0.3376 mL 0.8439 mL
100 mM 0.0270 mL 0.1350 mL 0.2700 mL 0.6751 mL
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2′,3′,5′-Triacetyl-5-azacytidine Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

2′,3′,5′-Triacetyl-5-azacytidine10302-78-0DNA MethyltransferaseDNMTsDNA MTasesprodrug5-AzacytidineInhibitorinhibitorinhibit

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