2'-Acetylacteoside (Standard)
2'-Acetylacteoside (Standard) is the analytical standard of 2'-Acetylacteoside (2'-AA) (HY-N0026). This product is intended for research and analytical applications. 2'-Acetylacteoside is a natural compound with oral activity and blood-brain barrier permeability. 2'-Acetylacteosideexhibits MAO‑B inhibitory activity (IC50 = 17.71 μM, Ki = 13.81 μM). 2'-Acetylacteoside downregulates the expression of RANK, TRAF6, NF‑κB, NFATc1 and IKKβ, disrupts the RANKL/RANK interaction, blocks downstream signaling pathways, and increases the level of phosphorylated Akt. 2'-Acetylacteoside possesses potent anti-osteoclastogenic, anti-bone resorptive, pro-neurogenic, neuroprotective and antioxidant activities. 2'-Acetylacteoside can be used in the research of osteoporosis, ischemic stroke and Parkinson's disease.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- CAS 番号: 94492-24-7
- 分子式: C31H38O16
- 分子量:666.62
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保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Product Information
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化学情報
- 純度とドキュメンテーション
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Help & FAQs
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HY-N0026
2'-AcetylacteosideNatural Compound -
HY-N0022
IsoacteosideNatural Product -
HY-N0528
LinarinAChE Inhibitor -
HY-103596
Thalidomide-4-OHCereblon Ligand -
HY-W015600
2-AcetamidophenolFerroptosis Regulator -
HY-N1067
XanthohumolCOX Inhibitor -
HY-N0015
AstragalinNF-κB Inhibitor -
HY-N0791
TectoridinPhytoestrogen -
HY-N0367
Trans-AnetholeEndogenous Metabolite -
HY-N0321
Caftaric acidAnti-apoptotic Agent -
HY-N0791R
Tectoridin (Standard)Phytoestrogen
Product Information
説明
アプリケーション
The compound is the grade of analytical standard, which is the reference standard supplied assay. It is commonly used in qualitative, quantitative and methodological research experiments in HPLC, GC and MS.
化学情報
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CAS 番号 94492-24-7
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分子量 666.62
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分子式 C31H38O16
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SMILES
OC1=CC=C(/C=C/C(O[C@H]2[C@H](O[C@]3([H])O[C@@H](C)[C@H](O)[C@@H](O)[C@H]3O)[C@@H](OC(C)=O)[C@H](OCCC4=CC=C(O)C(O)=C4)O[C@@H]2CO)=O)C=C1O
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別名
2'-AA (Standard)
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Structure Classification
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Initial Source
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
参考文献
[1]. Li Y, Li N, Zhao X, et al. Beneficial effect of 2'-acetylacteoside on ovariectomized mice via modulating the function of bone resorption. Biomed Pharmacother. 2020;131:110747. [Content Brief]
[2]. Wang M, et al. 2-Acetylacteoside improves recovery after ischemic stroke by promoting neurogenesis via the PI3K/Akt pathway. Free Radic Biol Med. 2024;225:415-429. [Content Brief]
[3]. Zhai X, et al. Evaluation of the Neuroprotective Effect of Total Glycosides of Cistanche deserticola and Investigation of Novel Brain-Targeting Natural MAO-B Inhibitors. ACS Chem Neurosci. 2024 Dec 18;15(24):4544-4558. [Content Brief]
[4]. He ZD, et al. Antioxidant activity of phenylethanoid glycosides from Brandisia hancei. J Ethnopharmacol. 2000 Aug;71(3):483-6. [Content Brief]
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
2'-Acetylacteoside (Standard) 関連分類
HY-N0026R 関連分類
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