2-Amino-5-fluorophenol
Based on 1 Customer Validation
2-Amino-5-fluorophenol is an isomer of aminofluorophenol and also a HONO generator. 2-Amino-5-fluorophenol reacts with nitrogen dioxide (NO2) via two pathways to form nitrous acid (HONO): hydrogen abstraction from the hydroxyl group and hydrogen abstraction from the amino group, with both the amino and hydroxyl groups participating in the reaction in the transition state.
For research use only. We do not sell to patients.
- CAS No.: 53981-24-1
- Formula: C6H6FNO
- Molecular Weight:127.12
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Storage:
4°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Description
In Vitro
2-Amino-5-fluorophenol reacts with nitrogen dioxide (NO2) via two pathways to form nitrous acid (HONO): hydrogen abstraction from the hydroxyl group and hydrogen abstraction from the amino group, with both the amino and hydroxyl groups participating in the reaction in the transition state[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 53981-24-1
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Appearance Solid
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Molecular Weight 127.12
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Formula C6H6FNO
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Color Brown to dark brown
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SMILES
FC1=CC(O)=C(N)C=C1
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Synonyms
4-Fluoro-2-hydroxyaniline
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
4°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
Solvent & Solubility
In Vitro:
DMSO : 5.83 mg/mL (45.86 mM; ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:
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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Working solution concentration: 0.22 mg/mL
Purity & Documentation
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Data Sheet (271 KB)
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SDS (394 KB)
- English - EN (394 KB)
- Français - FR (394 KB)
- Deutsch - DE (394 KB)
- Norwegian - NO (394 KB)
- Español - ES (394 KB)
- Swedish - SV (394 KB)
- Italian - IT (394 KB)
- Korean - KR (394 KB)
- Portuguese - PT (394 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 7.8666 mL | 39.3329 mL | 78.6658 mL | 196.6646 mL |
| 5 mM | 1.5733 mL | 7.8666 mL | 15.7332 mL | 39.3329 mL | |
| 10 mM | 0.7867 mL | 3.9333 mL | 7.8666 mL | 19.6665 mL | |
| 15 mM | 0.5244 mL | 2.6222 mL | 5.2444 mL | 13.1110 mL | |
| 20 mM | 0.3933 mL | 1.9666 mL | 3.9333 mL | 9.8332 mL | |
| 25 mM | 0.3147 mL | 1.5733 mL | 3.1466 mL | 7.8666 mL | |
| 30 mM | 0.2622 mL | 1.3111 mL | 2.6222 mL | 6.5555 mL | |
| 40 mM | 0.1967 mL | 0.9833 mL | 1.9666 mL | 4.9166 mL |
2-Amino-5-fluorophenol Related Classifications
HY-W007345 Related Classifications
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