2-Amino-5-fluorophenol  (Synonyms: 4-Fluoro-2-hydroxyaniline)

2-Amino-5-fluorophenol is an isomer of aminofluorophenol and also a HONO generator. 2-Amino-5-fluorophenol reacts with nitrogen dioxide (NO₂) via two pathways to form nitrous acid (HONO): hydrogen abstraction from the hydroxyl group and hydrogen abstraction from the amino group, with both the amino and hydroxyl groups participating in the reaction in the transition state^[1].

2-Amino-5-fluorophenol reacts with nitrogen dioxide (NO2) via two pathways to form nitrous acid (HONO): hydrogen abstraction from the hydroxyl group and hydrogen abstraction from the amino group, with both the amino and hydroxyl groups participating in the reaction in the transition state^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

127.12

C₆H₆FNO

53981-24-1

Solid

Brown to dark brown

FC1=CC(O)=C(N)C=C1

Room temperature in continental US; may vary elsewhere.

4°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

• [1]. Scott Hewitt, et al. THE PRODUCTION OF HONO FROM THE REACTION BETWEEN NO2 AND AMINOFLUROPHENOL: AN EXPERIMENTAL AND THEORETICAL STUDY. 2021, JOHN HASENBEIN, CC-BY-NC-ND 4.0.