2-Chlorophenothiazine
Based on 1 Customer Validation
2-Chlorophenothiazine is a phenothiazine derivative. 2-Chlorophenothiazine has the activity of inhibiting DNA, RNA and protein synthesis. 2-Chlorophenothiazine is an intermediate in the synthesis of Chlorpromazine (HY-12708) and Perphenazine (HY-A0077).
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- CAS 番号: 92-39-7
- 分子式: C12H8ClNS
- 分子量:233.72
-
保管条件:
Store at room temperature 3 years.
In solvent -80°C, 2 years , -20°C, 1 year
生物活性
製品説明
Cellular Effect
|
Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| K562 | IC50 |
>100 μM
Compound: 14
|
Antiproliferative activity against human K562 cells after 48 hrs by hemocytometric analysis
Antiproliferative activity against human K562 cells after 48 hrs by hemocytometric analysis
|
[PMID: 21563750] |
化学情報
-
CAS 番号 92-39-7
-
性状 Solid
-
分子量 233.72
-
分子式 C12H8ClNS
-
SMILES
ClC(C=C1N2)=CC=C1SC3=C2C=CC=C3
-
輸送条件
Room temperature in continental US; may vary elsewhere.
-
保管条件
Store at room temperature 3 years
In solvent -80°C 2 years -20°C 1 year
溶剤 & 溶解度
体外:
DMSO : 25 mg/mL (106.97 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
純度とドキュメンテーション
-
データシート (269 KB)
-
SDS (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
-
取扱説明書 (2659 KB)
参考文献
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 4.2786 mL | 21.3931 mL | 42.7862 mL | 106.9656 mL |
| 5 mM | 0.8557 mL | 4.2786 mL | 8.5572 mL | 21.3931 mL | |
| 10 mM | 0.4279 mL | 2.1393 mL | 4.2786 mL | 10.6966 mL | |
| 15 mM | 0.2852 mL | 1.4262 mL | 2.8524 mL | 7.1310 mL | |
| 20 mM | 0.2139 mL | 1.0697 mL | 2.1393 mL | 5.3483 mL | |
| 25 mM | 0.1711 mL | 0.8557 mL | 1.7114 mL | 4.2786 mL | |
| 30 mM | 0.1426 mL | 0.7131 mL | 1.4262 mL | 3.5655 mL | |
| 40 mM | 0.1070 mL | 0.5348 mL | 1.0697 mL | 2.6741 mL | |
| 50 mM | 0.0856 mL | 0.4279 mL | 0.8557 mL | 2.1393 mL | |
| 60 mM | 0.0713 mL | 0.3566 mL | 0.7131 mL | 1.7828 mL | |
| 80 mM | 0.0535 mL | 0.2674 mL | 0.5348 mL | 1.3371 mL | |
| 100 mM | 0.0428 mL | 0.2139 mL | 0.4279 mL | 1.0697 mL |