2-Methoxyphenothiazine
Based on 1 Customer Validation
2-Methoxyphenothiazine (2-Methoxy-10H-phenothiazine) is a biochemical reagent that can be used in research fields such as life sciences or organic chemistry.
For research use only. We do not sell to patients.
- Purity: 99.61%
- CAS No.: 1771-18-2
- Formula: C13H11NOS
- Molecular Weight:229.30
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Storage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
Biological Activity
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| HT-1080 | EC50 |
1.748 μM
Compound: P23
|
Inhibition of erastin-induced ferroptosis in human HT-1080 cells assessed as cell viability incubated for 48 hrs by MTT assay
Inhibition of erastin-induced ferroptosis in human HT-1080 cells assessed as cell viability incubated for 48 hrs by MTT assay
|
[PMID: 33065375] |
| RBL-1 | IC50 |
0.02 μM
Compound: 30
|
In vitro inhibition of 5-lipoxygenase pathway in rat basophilic leukemia (RBL-1) cells
In vitro inhibition of 5-lipoxygenase pathway in rat basophilic leukemia (RBL-1) cells
|
[PMID: 2113951] |
2-Methoxyphenothiazine, as a mediator, can significantly enhance the decolorization efficiency of laccase from Trametes modesta toward various dyes, especially showing remarkable effect on Basic Red 9, but may produce precipitates when reacting with dyes[1].
2-Methoxyphenothiazine can serve as the active component of the catalyst, be supported on the surface of nanosilica through a coupling agent, and be used for the electrochemical intensified catalysis of the esterification reaction between acrylic acid and monohydric alcohols, achieving efficient conversion under mild conditions and showing good cycle stability[2].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 1771-18-2
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Appearance Solid
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Molecular Weight 229.30
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Formula C13H11NOS
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Color Off-white to gray
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SMILES
COC1=CC(NC2=CC=CC=C2S3)=C3C=C1
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Synonyms
2-Methoxy-10H-phenothiazine
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
DMSO : ≥ 100 mg/mL (436.11 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
* "≥" means soluble, but saturation unknown.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (272 KB)
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SDS (761 KB)
- English - EN (761 KB)
- Français - FR (761 KB)
- Deutsch - DE (761 KB)
- Norwegian - NO (761 KB)
- Español - ES (761 KB)
- Swedish - SV (761 KB)
- Italian - IT (761 KB)
- Korean - KR (761 KB)
- Portuguese - PT (761 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 4.3611 mL | 21.8055 mL | 43.6110 mL | 109.0275 mL |
| 5 mM | 0.8722 mL | 4.3611 mL | 8.7222 mL | 21.8055 mL | |
| 10 mM | 0.4361 mL | 2.1805 mL | 4.3611 mL | 10.9027 mL | |
| 15 mM | 0.2907 mL | 1.4537 mL | 2.9074 mL | 7.2685 mL | |
| 20 mM | 0.2181 mL | 1.0903 mL | 2.1805 mL | 5.4514 mL | |
| 25 mM | 0.1744 mL | 0.8722 mL | 1.7444 mL | 4.3611 mL | |
| 30 mM | 0.1454 mL | 0.7268 mL | 1.4537 mL | 3.6342 mL | |
| 40 mM | 0.1090 mL | 0.5451 mL | 1.0903 mL | 2.7257 mL | |
| 50 mM | 0.0872 mL | 0.4361 mL | 0.8722 mL | 2.1805 mL | |
| 60 mM | 0.0727 mL | 0.3634 mL | 0.7268 mL | 1.8171 mL | |
| 80 mM | 0.0545 mL | 0.2726 mL | 0.5451 mL | 1.3628 mL | |
| 100 mM | 0.0436 mL | 0.2181 mL | 0.4361 mL | 1.0903 mL |