2′-β-C-Methyl-2-methoxyadenosine
2′-β-C-Methyl-2-methoxyadenosine is an adenosine analogue. Adenosine analogs mostly act as smooth muscle vasodilators and have also been shown to inhibit cancer progression. The popular products in this series are adenosine phosphate, Acadesine (HY-13417), Clofarabine (HY-A0005), Fludarabine phosphate (HY-B0028) and Vidarabine (HY-B0277).
For research use only. We do not sell to patients.
- CAS No.: 1829554-43-9
- Formula: C12H17N5O5
- Molecular Weight:311.29
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
|
Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| CCRF-CEM | CC50 |
>100 μM
Compound: 26
|
Cytotoxicity against human CEM cells after 6 days by trypan blue exclusion assay
Cytotoxicity against human CEM cells after 6 days by trypan blue exclusion assay
|
[PMID: 26819659] |
| Huh-7 | CC50 |
>10 μM
Compound: 26
|
Cytotoxicity against human HuH7 cells infected with HCV assessed as reduction in cellular rRNA level after 96 hrs by qRT-PCR analysis
Cytotoxicity against human HuH7 cells infected with HCV assessed as reduction in cellular rRNA level after 96 hrs by qRT-PCR analysis
|
[PMID: 26819659] |
| PBMC | CC50 |
>100 μM
Compound: 26
|
Cytotoxicity against human PBMC after 6 days by trypan blue exclusion assay
Cytotoxicity against human PBMC after 6 days by trypan blue exclusion assay
|
[PMID: 26819659] |
| Vero | CC50 |
>100 μM
Compound: 26
|
Cytotoxicity against African green monkey Vero cells after 3 days by hemocytometry
Cytotoxicity against African green monkey Vero cells after 3 days by hemocytometry
|
[PMID: 26819659] |
Chemical Information
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CAS No. 1829554-43-9
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Molecular Weight 311.29
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Formula C12H17N5O5
-
SMILES
OC[C@@H]1[C@@H](O)[C@](O)(C)[C@H](N2C=NC3=C2N=C(OC)N=C3N)O1
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Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)