2. Neuronal Signaling Anti-infection
  3. Tau Protein HBV
  4. 3'-DMTr-dG(iBu)

3'-DMTr-dG(iBu) is a nucleoside for the synthesis of nucleic acid, such as antiviral agents used in the research of viral infection (HBV, HDV), and oligonucleotides against Alzheimer’s disease and other tauopathies.

For research use only. We do not sell to patients.

3'-DMTr-dG(iBu)

3'-DMTr-dG(iBu) Chemical Structure

CAS No. : 140839-24-3

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3'-DMTr-dG(iBu) Related Antibodies

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Description

3'-DMTr-dG(iBu) is a nucleoside for the synthesis of nucleic acid, such as antiviral agents used in the research of viral infection (HBV, HDV), and oligonucleotides against Alzheimer’s disease and other tauopathies[1].

IC50 & Target

Tau protein, HBV, HCV[1]
Molecular Weight

839.92

Formula

C44H54N7O8P
CAS No.
Appearance

Powder

SMILES

CC(C)N(C(C)C)P(OCCC#N)OC[C@@H](O[C@](N1C2=C(C(N=C(N2)NC(C(C)C)=O)=O)N=C1)([H])C3)[C@H]3OC(C4=CC=C(C=C4)OC)(C5=CC=CC=C5)C6=CC=C(C=C6)OC
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 25 mg/mL (29.76 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.1906 mL 5.9529 mL 11.9059 mL
5 mM 0.2381 mL 1.1906 mL 2.3812 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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In Vivo Dissolution Calculator
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Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 1.1906 mL 5.9529 mL 11.9059 mL 29.7647 mL
5 mM 0.2381 mL 1.1906 mL 2.3812 mL 5.9529 mL
10 mM 0.1191 mL 0.5953 mL 1.1906 mL 2.9765 mL
15 mM 0.0794 mL 0.3969 mL 0.7937 mL 1.9843 mL
20 mM 0.0595 mL 0.2976 mL 0.5953 mL 1.4882 mL
25 mM 0.0476 mL 0.2381 mL 0.4762 mL 1.1906 mL
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3'-DMTr-dG(iBu) Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

3'-DMTr-dG(iBu)140839-24-3Tau ProteinHBVHepatitis B virusInfectionvirusnucleic acidtauopathiesAlzheimer’s diseaseInhibitorinhibitorinhibit

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