4-Arm-PEG10000-DBCO
Based on 1 Customer Validation
4-Arm-PEG10000-DBCO is a four-armed PEG derivative. The core structure of 4-Arm-PEG10000-DBCO consists of four PEG chains, each modified at the end with a diphenylcyclooctyne (DBCO) group. 4-Arm-PEG10000-DBCO can be used for bioconjugation and drug delivery.
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- Pureté: 90.0%
- CAS No.: 1799770-02-7
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Stockage:Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
Activité biologique
The structure of PEG-DBCO comprises two key parts that work synergistically:
DBCO group: A highly reactive cyclic alkyne structure capable of undergoing copper-free click chemistry (azido-alkyne cycloaddition) with molecules containing an azide group (-N3).
PEG chain: Acting as a hydrophilic spacer, it forms a hydration layer on the particle surface, reducing nonspecific adsorption and immune system recognition and clearance, thus prolonging the carrier's circulation time in vivo.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 1799770-02-7
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Appearance Solid
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Color White to off-white
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SMILES
O=C(CCC(N1CC(C=CC=C2)=C2C#CC3=C1C=CC=C3)=O)NCCOCCOCC(COCCOCCNC(CCC(N4CC(C=CC=C5)=C5C#CC6=C4C=CC=C6)=O)=O)(COCCOCCNC(CCC(N7C8=C(C#CC9=C(C7)C=CC=C9)C=CC=C8)=O)=O)COCCOCCNC(CCC(N%10C%11=C(C#CC%12=C(C%10)C=CC=C%12)C=CC=C%11)=O)=O.[n].[n].[n].[n]
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Powder -20°C 3 years In solvent -80°C 6 months -20°C 1 month
Solvant et solubilité
DMSO : 100 mg/mL (Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Pureté et documentation
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Fiche technique (248 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Instruction de manipulation (2659 KB)
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)