4-Chlorobutanal
Based on 1 Customer Validation
4-Chlorobutanal is a PROTAC linker that can be used in the synthesis of PROTACs.
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- CAS No.: 6139-84-0
- Formule: C4H7ClO
- Masse moléculaire:106.55
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Stockage:
-20°C, stored under nitrogen
* In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)
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Activité biologique
PROTACs contain two different ligands connected by a linker; one is a ligand for an E384 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 6139-84-0
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Appearance Liquid
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Masse moléculaire 106.55
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Formule C4H7ClO
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Color Colorless to light yellow
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SMILES
O=CCCCCl
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
-20°C, stored under nitrogen
* In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)
Solvant et solubilité
DMSO : 100 mg/mL (938.53 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Pureté et documentation
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Fiche technique (239 KB)
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SDS (605 KB)
- English - EN (605 KB)
- Français - FR (605 KB)
- Deutsch - DE (605 KB)
- Norwegian - NO (605 KB)
- Español - ES (605 KB)
- Swedish - SV (605 KB)
- Italian - IT (605 KB)
- Korean - KR (605 KB)
- Portuguese - PT (605 KB)
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Instruction de manipulation (2659 KB)
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 9.3853 mL | 46.9263 mL | 93.8526 mL | 234.6316 mL |
| 5 mM | 1.8771 mL | 9.3853 mL | 18.7705 mL | 46.9263 mL | |
| 10 mM | 0.9385 mL | 4.6926 mL | 9.3853 mL | 23.4632 mL | |
| 15 mM | 0.6257 mL | 3.1284 mL | 6.2568 mL | 15.6421 mL | |
| 20 mM | 0.4693 mL | 2.3463 mL | 4.6926 mL | 11.7316 mL | |
| 25 mM | 0.3754 mL | 1.8771 mL | 3.7541 mL | 9.3853 mL | |
| 30 mM | 0.3128 mL | 1.5642 mL | 3.1284 mL | 7.8211 mL | |
| 40 mM | 0.2346 mL | 1.1732 mL | 2.3463 mL | 5.8658 mL | |
| 50 mM | 0.1877 mL | 0.9385 mL | 1.8771 mL | 4.6926 mL | |
| 60 mM | 0.1564 mL | 0.7821 mL | 1.5642 mL | 3.9105 mL | |
| 80 mM | 0.1173 mL | 0.5866 mL | 1.1732 mL | 2.9329 mL | |
| 100 mM | 0.0939 mL | 0.4693 mL | 0.9385 mL | 2.3463 mL |