4-Ethynylcyclohexanone
Based on 1 Customer Validation
4-Ethynylcyclohexanone is a PROTAC linker that can be used in the synthesis of PROTACs.
For research use only. We do not sell to patients.
- Purity: 99.69%
- CAS No.: 1549050-50-1
- Formula: C8H10O
- Molecular Weight:122.17
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Storage:
Store at room temperature 3 years.
In solvent -80°C, 2 years , -20°C, 1 year
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
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Help & FAQs
All PROTAC Linkers Isoforms
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Biological Activity
PROTACs contain two different ligands connected by a linker; one is a ligand for an E388 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 1549050-50-1
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Appearance Solid
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Molecular Weight 122.17
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Formula C8H10O
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Color Colorless to light yellow
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SMILES
O=C1CCC(C#C)CC1
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Store at room temperature 3 years
In solvent -80°C 2 years -20°C 1 year
Solvent & Solubility
DMSO : 100 mg/mL (818.53 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (242 KB)
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SDS (605 KB)
- English - EN (605 KB)
- Français - FR (605 KB)
- Deutsch - DE (605 KB)
- Norwegian - NO (605 KB)
- Español - ES (605 KB)
- Swedish - SV (605 KB)
- Italian - IT (605 KB)
- Korean - KR (605 KB)
- Portuguese - PT (605 KB)
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Handling Instructions (2659 KB)
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 8.1853 mL | 40.9266 mL | 81.8532 mL | 204.6329 mL |
| 5 mM | 1.6371 mL | 8.1853 mL | 16.3706 mL | 40.9266 mL | |
| 10 mM | 0.8185 mL | 4.0927 mL | 8.1853 mL | 20.4633 mL | |
| 15 mM | 0.5457 mL | 2.7284 mL | 5.4569 mL | 13.6422 mL | |
| 20 mM | 0.4093 mL | 2.0463 mL | 4.0927 mL | 10.2316 mL | |
| 25 mM | 0.3274 mL | 1.6371 mL | 3.2741 mL | 8.1853 mL | |
| 30 mM | 0.2728 mL | 1.3642 mL | 2.7284 mL | 6.8211 mL | |
| 40 mM | 0.2046 mL | 1.0232 mL | 2.0463 mL | 5.1158 mL | |
| 50 mM | 0.1637 mL | 0.8185 mL | 1.6371 mL | 4.0927 mL | |
| 60 mM | 0.1364 mL | 0.6821 mL | 1.3642 mL | 3.4105 mL | |
| 80 mM | 0.1023 mL | 0.5116 mL | 1.0232 mL | 2.5579 mL | |
| 100 mM | 0.0819 mL | 0.4093 mL | 0.8185 mL | 2.0463 mL |
4-Ethynylcyclohexanone Related Classifications
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