4-Hydroxy-6-methyl-2-pyrone
Based on 1 Customer Validation
4-Hydroxy-6-methyl-2-pyrone is an intermediate. 4-Hydroxy-6-methyl-2-pyrone can be used for the synthesis of Hispidin (HY-100618) and antibacterial agents. 4-Hydroxy-6-methyl-2-pyrone can be used for research on bacterial infections, fungal infections, pancreatic adenocarcinoma, squamous cell carcinoma, and tuberculosis.
Nos produits utilisent uniquement pour la recherche. Nous ne vendons pas aux patients.
- Pureté : 99.77%
- CAS No.: 675-10-5
- Formule: C6H6O3
- Masse moléculaire:126.11
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Stockage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Activité biologique
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Chemical Information
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Solvant et solubilité
- Protocole
- Pureté et documentation
- Références
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Help & FAQs
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Rose oxideMonoterpene Compound -
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(Tetrahydro-2H-pyran-4-yl)methanolHepatitis Virus Inhibitor
Activité biologique
Description
Cellular Effect
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Cell Line
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Type | Value | Description | References |
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| Vero | IC50 |
> 250 μM
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Cytotoxicity against african green monkey kidney Vero cells assessed as reduction in cell viability incubated for 72 hrs by MTT assay.
Cytotoxicity against african green monkey kidney Vero cells assessed as reduction in cell viability incubated for 72 hrs by MTT assay.
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slct.202404988 |
In Vitro
The 4-hydroxy-6-methyl-2-pyrone derivative 4e exhibits potent anti-tuberculosis activity against M. tuberculosis H37Rv, with an MIC of 3.12 μg/mL[4].
The 4-hydroxy-6-methyl-2-pyrone derivative 4e exhibits significant antimicrobial activity against S. aureus (MIC = 0.3125 mg/mL) and A. niger (MIC = 0.0195 mg/mL)[4].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. Further protocols information, click here.
Chemical Information
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CAS No. 675-10-5
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Appearance Solid
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Masse moléculaire 126.11
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Formule C6H6O3
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Color White to off-white
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SMILES
O=C1C=C(O)C=C(C)O1
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Solvant et solubilité
In Vitro:
DMSO : 100 mg/mL (792.96 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Protocole
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Research Protocol for Infectious Diseases
Infectious-disease experiments test how pathogens interact with host barriers, innate immune receptors, inflammatory signaling, pathogen replication, and tissue injury; pattern-recognition receptors such as TLRs, RIG-I-like receptors, NOD-like receptors, and inflammasomes detect microbial molecules and activate NF-κB, interferon, and cytokine responses. The central hypothesis is that infection severity reflects the balance between pathogen burden and host response: protective inflammation restricts pathogen growth, whereas excessive or mislocalized inflammation contributes to tissue damage and disease phenotype. Unresolved questions include which host pathways are protective versus pathogenic, why some infection models fail to translate to human disease, and which combined readouts best predict clinically relevant infection outcomes.
Pureté et documentation
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Fiche technique (274 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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Instruction de manipulation (2659 KB)
Références
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
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| DMSO | 1 mM | 7.9296 mL | 39.6479 mL | 79.2959 mL | 198.2396 mL |
| 5 mM | 1.5859 mL | 7.9296 mL | 15.8592 mL | 39.6479 mL | |
| 10 mM | 0.7930 mL | 3.9648 mL | 7.9296 mL | 19.8240 mL | |
| 15 mM | 0.5286 mL | 2.6432 mL | 5.2864 mL | 13.2160 mL | |
| 20 mM | 0.3965 mL | 1.9824 mL | 3.9648 mL | 9.9120 mL | |
| 25 mM | 0.3172 mL | 1.5859 mL | 3.1718 mL | 7.9296 mL | |
| 30 mM | 0.2643 mL | 1.3216 mL | 2.6432 mL | 6.6080 mL | |
| 40 mM | 0.1982 mL | 0.9912 mL | 1.9824 mL | 4.9560 mL | |
| 50 mM | 0.1586 mL | 0.7930 mL | 1.5859 mL | 3.9648 mL | |
| 60 mM | 0.1322 mL | 0.6608 mL | 1.3216 mL | 3.3040 mL | |
| 80 mM | 0.0991 mL | 0.4956 mL | 0.9912 mL | 2.4780 mL | |
| 100 mM | 0.0793 mL | 0.3965 mL | 0.7930 mL | 1.9824 mL |
4-Hydroxy-6-methyl-2-pyrone Related Classifications
HY-Y1634 Related Classifications
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