5,6-trans-Bimatoprost
5,6-trans-Bimatoprost is the isomer of Bimatoprost (HY-B0191), and can be used as an experimental control. Bimatoprost is a prostaglandin analogue that can be used in studies of ocular hypertension and glaucoma and also has anti-fat formation effects.
For research use only. We do not sell to patients.
- CAS No.: 1163135-95-2
- Formula: C25H37NO4
- Molecular Weight:415.57
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Protocols
- Purity & Documentation
- References
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Help & FAQs
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HY-113254
13,14-Dihydro-15-keto-PGE25-HT Modulator -
HY-113358S
6-keto Prostaglandin F1α-d4Stable Isotope -
HY-113459S1
13,14-Dihydro-15-keto Prostaglandin F2α-d4Stable Isotope -
HY-135163
trans-Latanoprostthe Trans Isomer of Latanoprost -
HY-101952S1
Prostaglandin E2-d9Stable Isotope -
HY-113756
trans-Latanoprost acidIsomer -
HY-126986S
Tetranor-PGDM-d6Stable Isotope -
HY-113459S
Prostaglandin F1a-d9Stable Isotope -
HY-113042S
Prostaglandin B2-d4Stable Isotope -
HY-113041S
Prostaglandin A2-d4Stable Isotope -
HY-W701877
Latanoprost tris(triethylsilyl) ether
Biological Activity
Description
Chemical Information
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CAS No. 1163135-95-2
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Molecular Weight 415.57
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Formula C25H37NO4
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SMILES
O=C(NCC)CCC/C=C/C[C@@H]1[C@@H](/C=C/[C@@H](O)CCC2=CC=CC=C2)[C@H](O)C[C@@H]1O
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Synonyms
5,6-trans-AGN 192024
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Protocols
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Research Protocol for Cardiovascular Diseases
Cardiovascular disease can be modeled as maladaptive cardiac remodeling, where ischemic injury or pressure overload activates inflammatory signaling, fibroblast activation, extracellular-matrix deposition, cardiomyocyte hypertrophy, vascular remodeling, and progressive ventricular dysfunction. The TGF-β/SMAD axis is a central profibrotic pathway after myocardial injury and pressure overload, while innate immune and cytokine pathways regulate leukocyte recruitment, scar formation, and adverse remodeling. Key unresolved questions include which inflammatory signals are reparative versus harmful, when fibrosis is protective versus maladaptive, and whether pathway inhibition improves function without weakening necessary infarct healing or compensatory remodeling.
Purity & Documentation
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Data Sheet (268 KB)
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SDS (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
[1]. Park J, et al. Changes to upper eyelid orbital fat from use of topical bimatoprost, travoprost, and latanoprost. Jpn J Ophthalmol. 2011 Jan;55(1):22-7. [Content Brief]
[2]. Filippopoulos T, et al. Periorbital changes associated with topical bimatoprost. Ophthal Plast Reconstr Surg. 2008 Jul-Aug;24(4):302-7. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
5,6-trans-Bimatoprost Related Classifications
HY-B0191A Related Classifications
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