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Cat. No.: HY-144124

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5-C-heptyl-DNJ

5-heptyl-DNJ is a potent GAA agonist with a K_i of 0.0047 μM. 5-C-heptyl-DNJ increases GAA activities by chaperrone effects.

For research use only. We do not sell to patients.

CAS No.: 2734265-63-3
Formula: C₁₃H₂₇NO₄
Molecular Weight:261.36

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (265 KB)

5-C-heptyl-DNJ Chemical Structure

CAS No.: 2734265-63-3

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- IC₅₀ & Target
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

Description

5-heptyl-DNJ is a potent GAA agonist with a K_i of 0.0047 μM. 5-C-heptyl-DNJ increases GAA activities by chaperrone effects^[1].

IC₅₀ & Target

Ki: 0.0047 μM (GAA)^[1]

Chemical Information

CAS No. 2734265-63-3
Molecular Weight 261.36
Formula C₁₃H₂₇NO₄
SMILES

CCCCCCC[C@]1([C@H]([C@@H]([C@H](CN1)O)O)O)CO
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (265 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Atsushi Kato, et al. 5- C-Branched Deoxynojirimycin: Strategy for Designing a 1-Deoxynojirimycin-Based Pharmacological Chaperone with a Nanomolar Affinity for Pompe Disease. J Med Chem. 2022 Feb 10;65(3):2329-2341. [Content Brief]

Calculators

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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