5'-O-DMT-5-Ethynyl-2'-deoxyuridine 3'-CE phosphoramidite
Based on 1 Customer Validation
5'-O-DMT-5-Ethynyl-2'-deoxyuridine 3'-CE phosphoramidite is a phosphorite monomer that can be used in the synthesis of oligonucleotides.
For research use only. We do not sell to patients.
- Purity : 98.09%
- CAS No.: 188411-06-5
- Formula: C50H57N6O9P
- Molecular Weight:917.00
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Storage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
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Help & FAQs
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Biological Activity
Description
Chemical Information
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CAS No. 188411-06-5
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Appearance Solid
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Molecular Weight 917.00
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Formula C50H57N6O9P
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Color White to off-white
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SMILES
COC(C=C1)=CC=C1C(C2=CC=CC=C2)(OC[C@@H]3[C@@H](OP(OCCC#N)N(C(C)C)C(C)C)C[C@H](N4C=C(C(NC(C5=CC=CC=C5)=O)=NC4=O)COCCC#N)O3)C6=CC=C(C=C6)OC
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
In Vitro:
DMSO : 100 mg/mL (109.05 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
In Vivo:
Select the appropriate dissolution method based on your experimental animal and administration route.
- For the following dissolution methods, please ensure to first prepare a clear stock solution using an In Vitro approach and then sequentially add co-solvents:
- To ensure reliable experimental results, the clarified stock solution can be appropriately stored based on storage conditions. As for the working solution for In Vivo experiments, it is recommended to prepare freshly and use it on the same day.
- The percentages shown for the solvents indicate their volumetric ratio in the final prepared solution. If precipitation or phase separation occurs during preparation, heat and/or sonication can be used to aid dissolution.
In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:
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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Please enter your animal formula composition:
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%DMSO +
Recommended: Keep the proportion of DMSO in working solution below 2% if your animal is weak.
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%+
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+%Tween-80 + +
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%Saline +
The co-solvents required include: DMSO, . All of co-solvents are available by MedChemExpress (MCE). , Tween 80. All of co-solvents are available by MedChemExpress (MCE).
Working solution concentration: 0.22 mg/mL
Method for preparing stock solution: mg drug dissolved in μL DMSO. Stock solution concentration: mg/mL.
1. Take μL DMSO stock solution;
2. Add μL .
μL , mix evenly;
3. Then add μL Tween 80, mix evenly;
4. Then add μL
Please ensure that the stock solution in the first step is dissolved to a clear state, and add co-solvents in sequence. You can use ultrasonic heating (ultrasonic cleaner, recommended frequency 20-40 kHz), vortexing, etc. to assist dissolution.
Purity & Documentation
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Data Sheet (255 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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Handling Instructions (2659 KB)
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 1.0905 mL | 5.4526 mL | 10.9051 mL | 27.2628 mL |
| 5 mM | 0.2181 mL | 1.0905 mL | 2.1810 mL | 5.4526 mL | |
| 10 mM | 0.1091 mL | 0.5453 mL | 1.0905 mL | 2.7263 mL | |
| 15 mM | 0.0727 mL | 0.3635 mL | 0.7270 mL | 1.8175 mL | |
| 20 mM | 0.0545 mL | 0.2726 mL | 0.5453 mL | 1.3631 mL | |
| 25 mM | 0.0436 mL | 0.2181 mL | 0.4362 mL | 1.0905 mL | |
| 30 mM | 0.0364 mL | 0.1818 mL | 0.3635 mL | 0.9088 mL | |
| 40 mM | 0.0273 mL | 0.1363 mL | 0.2726 mL | 0.6816 mL | |
| 50 mM | 0.0218 mL | 0.1091 mL | 0.2181 mL | 0.5453 mL | |
| 60 mM | 0.0182 mL | 0.0909 mL | 0.1818 mL | 0.4544 mL | |
| 80 mM | 0.0136 mL | 0.0682 mL | 0.1363 mL | 0.3408 mL | |
| 100 mM | 0.0109 mL | 0.0545 mL | 0.1091 mL | 0.2726 mL |
5'-O-DMT-5-Ethynyl-2'-deoxyuridine 3'-CE phosphoramidite Related Classifications
HY-48873 Related Classifications
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