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Cat. No.: HY-N9134

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5-O-Methylgenistein

(Synonyms: Isoprunetin)

5-O-Methylgenistein (Isoprunetin) is an isoflavone that can be isolated from M. amurensis wood. 5-O-Methylgenistein inhibits β-gal activityy induced by 17β-Estradiol (HY-B0141) in yeast.

For research use only. We do not sell to patients.

CAS No.: 4569-98-6
Formula: C₁₆H₁₂O₅
Molecular Weight:284.26

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (266 KB)

5-O-Methylgenistein Chemical Structure

CAS No.: 4569-98-6

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Use of MCE Products

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Biological Activity
- Description
- Cellular Effect
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

Description

5-O-Methylgenistein (Isoprunetin) is an isoflavone that can be isolated from M. amurensis wood. 5-O-Methylgenistein inhibits β-gal activityy induced by 17β-Estradiol (HY-B0141) in yeast^[1]^[2].

Cellular Effect

Cell Line	Type	Value	Description	References
RAW264.7	IC₅₀	>1 μM Compound: 16	Inhibition of LPS-induced nitric oxide production in mouse RAW264.7 cells pretreated for 1 hr followed by LPS-stimulation and measured after 24 hrs by Griess assay Inhibition of LPS-induced nitric oxide production in mouse RAW264.7 cells pretreated for 1 hr followed by LPS-stimulation and measured after 24 hrs by Griess assay	[PMID: 29932657]

Chemical Information

CAS No. 4569-98-6
Molecular Weight 284.26
Formula C₁₆H₁₂O₅
SMILES

O=C1C(C2=CC=C(O)C=C2)=COC3=CC(O)=CC(OC)=C13
Synonyms

Isoprunetin
Structure Classification
- Flavonoids
- Isoflavones
Initial Source
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (266 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Kulesh, N.I., et al. Minor polyphenols from Maackia amurensis wood. Chem Nat Compd 44, 712–714 (2008).

[2]. Pinto B, et al. Estradiol-antagonistic activity of phenolic compounds from leguminous plants. Phytother Res. 2008 Mar;22(3):362-6. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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