Bometolol Hydrochloride
Bometolol Hydrochloride is a beta-adrenergic blocking agent, used for the research of cardiovascular disease.
For research use only. We do not sell to patients.
- CAS No.: 65023-16-7
- Formula: C25H33ClN2O7
- Molecular Weight:508.99
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
All Adrenergic Receptor Isoforms
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Biological Activity
Beta-adrenergic receptor[1]
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 65023-16-7
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Molecular Weight 508.99
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Formula C25H33ClN2O7
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SMILES
O=C1NC2=C(C(OCC(O)CNCCC3=CC=C(OC)C(OC)=C3)=CC=C2OCC(C)=O)CC1.[H]Cl
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Protocol
Rats[1]
In the acute experments, normal female Donryu strain (DON, 14-15 weeks, 250-270 g), and SHR (17-18 weeks, 180-200 g), DOC (7-9 weeks, 180-210 g), and CLIP (7-9 weeks, 180-210 g) hypertensive rats are used. Bometolol hydrochloride is dissolved in H2O and 0.01% Tween 80 solution at a volume of 5 mL/kg body weight for the acute and subchronic studies, respectively. The doses are in terms of the free base. The solution is administratered orally by a gastric tube. In the acute experiment, H2O (5 mL/kg) is giver to the control groups. In the subchronic experment, the drug is administered once a day for 5 weeks, 5 days per week, and Tween 80 solution (5 mL/kg) is given to the control groups[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)