HIV-1 integrase inhibitor 4
HIV-1 integrase inhibitor 4 is a HIV-1 integrase strand transfer (INST) inhibitor with an IC50 of 3.7 nM.
For research use only. We do not sell to patients.
- CAS No.: 1638504-66-1
- Formula: C24H20F2N4O5S
- Molecular Weight:514.50
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
IC50: 3.7 nM (INST)[1]
HIV-1 integrase inhibitor 4 (compound 4f) is a HIV-1 integrase strand transfer (INST) inhibitor with an IC50 of 3.7 nM. HIV-1 integrase inhibitor 4 shows potent activity against recombinant HIV IN in biochemical assays and good efficacy in assays done in cell culture against a broad panel of viral mutants carrying the major RAL and DTG IN resistance mutations[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 1638504-66-1
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Molecular Weight 514.50
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Formula C24H20F2N4O5S
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SMILES
NC(C1=CC(CCS(=O)(C2=CC=CC=C2)=O)=CN=C1N3O)=C(C(NCC4=CC=C(F)C=C4F)=O)C3=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)