LY 222306
LY 222306 is a glycinamide ribonucleotide formyltransferase (GARFT) inhibitor with a Ki of 0.77 nM.
For research use only. We do not sell to patients.
- CAS No.: 154446-98-7
- Formula: C19H23N5O7
- Molecular Weight:433.42
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
Ki: 0.77 nM (GARFT)[1]
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| CCRF-CEM | IC50 |
27 nM
Compound: 12
|
In vitro antitumor activity was assessed from rate of cell growth of CCRF/CEM cell line
In vitro antitumor activity was assessed from rate of cell growth of CCRF/CEM cell line
|
[PMID: 8027993] |
Chemical Information
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CAS No. 154446-98-7
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Molecular Weight 433.42
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Formula C19H23N5O7
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SMILES
O=C1C2=C(NCC(CCC(O3)=CC=C3C(N[C@@H](CCC(O)=O)C(O)=O)=O)C2)N=C(N)N1
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)