1. GPCR/G Protein
    Neuronal Signaling
  2. Opioid Receptor
  3. MCOPPB triHydrochloride

MCOPPB triHydrochloride (Synonyms: MCOPPB 3HCl)

Cat. No.: HY-13101 Purity: 99.35%
Handling Instructions

MCOPPB 3Hcl is a nociceptin receptor agonist with pKi of 10.07; weaker activity at other opioid receptors.

For research use only. We do not sell to patients.

MCOPPB triHydrochloride Chemical Structure

MCOPPB triHydrochloride Chemical Structure

CAS No. : 1108147-88-1

Size Stock
10 mM * 1  mL in DMSO Get quote
5 mg USD 96 Get quote
10 mg USD 168 Get quote
25 mg USD 336 Get quote
50 mg USD 540 Get quote
100 mg USD 960 Get quote

* Please select Quantity before adding items.

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Description

MCOPPB 3Hcl is a nociceptin receptor agonist with pKi of 10.07; weaker activity at other opioid receptors. IC50 value: 10.07 (pKi) Target: nociceptin receptor MCOPPB trihydrochloride is a trihydrochloride form of MCOPPB that is a new nonpeptide nociceptin/orphanin FQ peptide (NOP)-receptor agonist with a pKi of 10.07 ± 0.01 for the human NOP receptor.

Molecular Weight

518.01

Formula

C₂₆H₄₃Cl₃N₄

CAS No.

1108147-88-1

SMILES

CC1(N2CCC(N3C4=CC=CC=C4N=C3[[email protected]]5CNCCC5)CC2)CCCCCCC1.[H]Cl.[H]Cl.[H]Cl

Shipping

Room temperature in continental US; may vary elsewhere.

Storage
Powder -20°C 3 years
  4°C 2 years
In solvent -80°C 6 months
  -20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 100 mg/mL (193.05 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.9305 mL 9.6523 mL 19.3046 mL
5 mM 0.3861 mL 1.9305 mL 3.8609 mL
10 mM 0.1930 mL 0.9652 mL 1.9305 mL
*Please refer to the solubility information to select the appropriate solvent.
In Vivo:
  • 1.

    Add each solvent one by one:  10% DMSO    40% PEG300    5% Tween-80    45% saline

    Solubility: ≥ 2.5 mg/mL (4.83 mM); Clear solution

  • 2.

    Add each solvent one by one:  10% DMSO    90% (20% SBE-β-CD in saline)

    Solubility: ≥ 2.5 mg/mL (4.83 mM); Clear solution

  • 3.

    Add each solvent one by one:  10% DMSO    90% corn oil

    Solubility: ≥ 2.5 mg/mL (4.83 mM); Clear solution

*All of the co-solvents are provided by MCE.
References
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This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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Keywords:

MCOPPB triHydrochlorideMCOPPB 3HClOpioid ReceptorInhibitorinhibitorinhibit

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Product Name:
MCOPPB triHydrochloride
Cat. No.:
HY-13101
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