country

Product Name	Size / Unit Price	Qty

Total: USD 0.00 Checkout

Cat. No.: HY-10886

Copy Link Print Information

MCOPPB

1 Cited Publications

Customer Review

Based on 1 publication(s) in Google Scholar

MCOPPB is an orally active and selective agonist of Nociceptin/Orphanin FQ–Receptor. MCOPPB inhibits signaling through the NOP receptor in the mouse brain. MCOPPB is used in anxiety disorders research.

For research use only. We do not sell to patients.

CAS No.: 1028969-49-4
Formula: C₂₆H₄₀N₄
Molecular Weight:408.62

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (271 KB)

MCOPPB Chemical Structure

CAS No.: 1028969-49-4

Size

Price

Stock

Quantity

Amount: USD 0.00

* Please select Quantity before adding items.

Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- Cellular Effect
Chemical Information
Publications (1)
Purity & Documentation
References
Calculators
Help & FAQs
Bioz

Biological Activity

Description

All Opioid Receptor Isoforms :

Cellular Effect

Cell Line	Type	Value	Description	References
CHO-K1	EC₅₀	34 nM Compound: 1, MCOPPB	Agonist activity at human mu opioid receptor expressed in CHOK1 cells by [35S]GTPgammaS binding Agonist activity at human mu opioid receptor expressed in CHOK1 cells by [35S]GTPgammaS binding	[PMID: 19125610]
CHO-K1	EC₅₀	4696 nM Compound: 1, MCOPPB	Agonist activity at human delta opioid receptor expressed in CHOK1 cells by [35S]GTPgammaS binding Agonist activity at human delta opioid receptor expressed in CHOK1 cells by [35S]GTPgammaS binding	[PMID: 19125610]
HEK293	EC₅₀	0.39 nM Compound: 1, MCOPPB	Agonist activity at human NOP receptor expressed in HEK293 cells by [35S]GTPgammaS binding Agonist activity at human NOP receptor expressed in HEK293 cells by [35S]GTPgammaS binding	[PMID: 19125610]
HEK293	EC₅₀	80 nM Compound: 1, MCOPPB	Agonist activity at human kappa opioid receptor expressed in HEK293 cells by [35S]GTPgammaS binding Agonist activity at human kappa opioid receptor expressed in HEK293 cells by [35S]GTPgammaS binding	[PMID: 19125610]

Chemical Information

CAS No. 1028969-49-4
Molecular Weight 408.62
Formula C₂₆H₄₀N₄
SMILES

CC1(N2CCC(N3C4=CC=CC=C4N=C3[C@H]5CNCCC5)CC2)CCCCCCC1
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Publications (1)

All

Sort by:

Journal Impact Factor

RSC Med Chem

Probing non-peptide agonists binding at the human nociceptin/orphanin FQ receptor: a molecular modelling study. [Abstract]

2024 Dec 10. PMID: 39790123

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (271 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Hirao A, et al. Pharmacological characterization of the newly synthesized nociceptin/orphanin FQ-receptor agonist 1-[1-(1-methylcyclooctyl)-4-piperidinyl]-2-[(3R)-3-piperidinyl]-1H-benzimidazole as an anxiolytic agent. J Pharmacol Sci. 2008 Mar;106(3):361-8. [Content Brief]

Calculators

Molarity Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

Dilution Calculator

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

100 mg

Get Quote In-stock