MLT-747
Based on 1 Customer Validation
MLT-747 is a potent, selective, allosteric inhibitor of MALT1, binds MALT1 in the allosteric Trp580 pocket, with an IC50 of 14 nM.
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- CAS No.: 2097853-86-4
- Formule: C20H21Cl2N7O3
- Masse moléculaire:478.33
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Stockage:
4°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Activité biologique
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Chemical Information
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Solvant et solubilité
- Pureté et documentation
- Références
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Help & FAQs
Activité biologique
IC50: 14 nM (MALT1)[1]
MLT-747 (0-20 μM) stabilizes cellular MALT1-W580S with an EC50 of 314 nM[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 2097853-86-4
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Appearance Solid
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Masse moléculaire 478.33
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Formule C20H21Cl2N7O3
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Color White to off-white
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SMILES
O=C(NC1=CC(Cl)=C(C(N2CCCC2)=O)N=C1)NC3=C([C@@H](OC)C)N4C(N=C3)=CC(Cl)=N4
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
4°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
Solvant et solubilité
DMSO : 100 mg/mL (209.06 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Pureté et documentation
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Fiche technique (270 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Instruction de manipulation (2659 KB)
Références
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.0906 mL | 10.4530 mL | 20.9061 mL | 52.2652 mL |
| 5 mM | 0.4181 mL | 2.0906 mL | 4.1812 mL | 10.4530 mL | |
| 10 mM | 0.2091 mL | 1.0453 mL | 2.0906 mL | 5.2265 mL | |
| 15 mM | 0.1394 mL | 0.6969 mL | 1.3937 mL | 3.4843 mL | |
| 20 mM | 0.1045 mL | 0.5227 mL | 1.0453 mL | 2.6133 mL | |
| 25 mM | 0.0836 mL | 0.4181 mL | 0.8362 mL | 2.0906 mL | |
| 30 mM | 0.0697 mL | 0.3484 mL | 0.6969 mL | 1.7422 mL | |
| 40 mM | 0.0523 mL | 0.2613 mL | 0.5227 mL | 1.3066 mL | |
| 50 mM | 0.0418 mL | 0.2091 mL | 0.4181 mL | 1.0453 mL | |
| 60 mM | 0.0348 mL | 0.1742 mL | 0.3484 mL | 0.8711 mL | |
| 80 mM | 0.0261 mL | 0.1307 mL | 0.2613 mL | 0.6533 mL | |
| 100 mM | 0.0209 mL | 0.1045 mL | 0.2091 mL | 0.5227 mL |
MLT-747 Related Classifications
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