1. Apoptosis
  2. MDM-2/p53

Milademetan (Synonyms: DS-3032)

Cat. No.: HY-101266 Purity: >92.0%
Handling Instructions

Mliademetan is a specific MDM2 inhibitor, a pharmaceutical composition for use in treating acute myeloid leukemia (AML).

For research use only. We do not sell to patients.

Milademetan Chemical Structure

Milademetan Chemical Structure

CAS No. : 1398568-47-2

Size Price Stock Quantity
10 mM * 1 mL in DMSO USD 898 In-stock
Estimated Time of Arrival: December 31
1 mg USD 220 In-stock
Estimated Time of Arrival: December 31
5 mg USD 660 In-stock
Estimated Time of Arrival: December 31
10 mg USD 1100 In-stock
Estimated Time of Arrival: December 31
50 mg   Get quote  
100 mg   Get quote  

* Please select Quantity before adding items.

Customer Review

  • Biological Activity

  • Technical Information

  • Purity & Documentation

  • References

Description

Mliademetan is a specific MDM2 inhibitor, a pharmaceutical composition for use in treating acute myeloid leukemia (AML).

IC50 & Target

MDM2[1].

Clinical Trial
Solvent & Solubility
In Vitro: 

10 mM in DMSO

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.6167 mL 8.0837 mL 16.1674 mL
5 mM 0.3233 mL 1.6167 mL 3.2335 mL
10 mM 0.1617 mL 0.8084 mL 1.6167 mL
*Please refer to the solubility information to select the appropriate solvent.
References
Molecular Weight

618.53

Formula

C₃₀H₃₄Cl₂FN₅O₄

CAS No.

1398568-47-2

SMILES

O=C(NC1=CC(Cl)=CC=C21)[[email protected]]32C4(CCC(C)(C)CC4)N[[email protected]@H](C(N[[email protected]@H]5CC[[email protected]@H](C(N)=O)OC5)=O)[[email protected]@H]3C6=CC=NC(Cl)=C6F

Storage
Powder -20°C 3 years
  4°C 2 years
In solvent -80°C 6 months
  -20°C 1 month
Shipping

Room temperature in continental US; may vary elsewhere

  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

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Inquiry Information

Product Name:
Milademetan
Cat. No.:
HY-101266
Quantity:

Milademetan

Cat. No.: HY-101266