Flavonoids

Quercetin-3,4-di-O-glucoside is a flavonoid that can be isolated from Allium cepa.

Jaceidin triacetate(compound 54) is a natural compound isolated formmarulabark.Jaceidin triacetatecan inhibitSARS-CoV-2 Mpro, with theIC₅₀of 11.9μM.Jaceidin triacetateinhibits the replication of Sars-Cov-2 Viral in Vero-E6 cells.

Barpisoflavone A is a natural product from Apios americana.

GB-2a is a bioflavonoids that can be isolated from Rheedia gardneriana. GB-2a has significant analgesic activity in mice with 58.9% inhibition.

Licoflavanone (3′-Prenylnaringenin) is a flavanone with antioxidant, anti-inflammatory and anticancer activities. Licoflavanone can be isolated from the leaf extract of Glycyrrhiza glabra. Licoflavanone downregulates the mTOR/PI3K/AKT signaling pathway to inhibit the proliferation, migration and invasion of cancer cells, while activates Bax, Bad and multiple caspase enzymes to induce apoptosis. Its anti-inflammatory effect is manifested by reducing the nuclear translocation of NF-κB, decreasing the phosphorylation levels of p38, JNK and ERK1/2, thereby inhibiting the expression of nitric oxide, proinflammatory cytokines, COX-2 and iNOS. Licoflavanone is used in studies on nasopharyngeal carcinoma and related mechanisms.

Formoxanthone A is an apoptosis inducing compound that can significantly reduce the viability of HeLa cells at 25 μM.

Chamaejasmenin D is an antimitotic and antifungal agent.

Lupalbigenin is a natural compound with anti-metastatic and pro-apoptotic effects.

6-Hydroxyapigenin 6-O-β-D-glucoside-7-O-β-D-glucuronide (compound 8) is a kind of flavonoid. 6-Hydroxyapigenin 6-O-β-D-glucoside-7-O-β-D-glucuronide can be isolated from the water extract of Carthamus tinctorius.

Erysubin A is a prenylated isoflavonoid that can be isolated from Erinacea anthyllis.

8-Lavandulylkaempferol is a flavonoid that can be isolated from Sophora flaWescens. 8-Lavandulylkaempferol exhibits cytotoxic activity against the KB epidermoid carcinoma cell line with an IC₅₀ of 15.1 μg/mL.

2(S)-7-Hydroxy-5,8,2'-trimethoxyflavanone is a natural flavanone compound.

7-O-Methyldihydrowogonin is a flavonoid that can be isolated from Andrographis paniculata.

Sideritoflavone is a flavonoid. Sideritoflavone can be isolated from Baccharis densiflora. Sideritoflavone is toxic to JIMT-1 breast cancer cells.

5,7,3',4'-Tetrahydroxy-6-methoxyflavanone-7-glucoside (compound4) can be isolated from the Salvia plebeia R.Br.

Parthenosin (Quercetin 3-O-β-D-glucuronide butyl ester) is a flavonoid, that can be isolated from the aerial parts of Calligoum polygonoides. Parthenosin shows cytotoxic activity against HepG2 and MCF-7 cell lines with IC₅₀ values of 60.46 and 61.4 μg/mL, respectively.

3'-Methoxy-3,5,4'-trihydroxyflavone-7-neohesperidoside is a flavonoid that can be isolated from Cleome droserifolia. 3'-Methoxy-3,5,4'-trihydroxyflavone-7-neohesperidoside has moderate hepatoprotective activity..

5-Hydroxysophoranone is a flavanone that can be isolated from the Erythrina subumbrans. 5-Hydroxysophoranone shows weak antibacterial activity against several strains of Streptococcus.

Erythrivarone A is an isoflavone that can be isolated from the stem bark of Erythrina variegate.