Papaveraceae Extract

5-Deoxycajanin (Compound 4) is a flavonoid and can be isolated from Eschscholtzia californica.

Sanguinarine (Sanguinarin) gluconate, a benzophenanthridine alkaloid, can stimulate apoptosis via activating the production of reactive oxygen species (ROS). Sanguinarine-induced apoptosis is associated with the activation of JNK and NF-κB.

N1,N10-Bis(p-coumaroyl)spermidine is a phenylpropanoid that can be isolated from Fagales pollen.

Aporeine (Aporheine) is an alkaloid that can be isolated from the aerial parts of p. rhoeas.

Sibiricine (Compound 8) is an isoquinoline alkaloid derived from the medicinal plant Corydalis crispa. Sibiricine has significant anti-inflammatory activity on TNF-α production by LPS-activated THP-1 cells.

(-)-Stylopine ((S)-Tetrahydrocoptisine) is an enantiomer of Stylopine (HY-N0924). Stylopine is a major alkaloid component of the leaf of Chelidonium majus.

Rhoeadine is an alkaloid. Rhoeadine is derived from natural Papaver setigerum.

Erythrodiol 3-O-palmitate is a natural product isolated from Dicranostigma leptopodum (Maxim) Fedde, Gentiana rhodantha Franch or Swertia kouitchensis. Erythrodiol 3-O-palmitate has antitumor activity, and inhibits the proliferation of K562 cells with the inhibition rate of 47% at 100 ug/mL.

Corycavine is an alkaloid that can be isolated from Corydalis remota.

Coulteropine is a natural alkaloid with antimicrobial activities.

(R)-(+)-Tetrahydroberberine is the isomer of (S)-(-)-Tetrahydroberberine (HY-N1418), and can be used as an experimental control. (S)-(-)-Tetrahydroberberine is an alkaloid and intermediate in the biosynthesis of berberine with insecticidal activity.

(S)-(-)-Tetrahydroberberine is an alkaloid and intermediate in the biosynthesis of berberine with insecticidal activity.

2,3,5,6-Tetramethoxyaporphine is an antitussive agent, a medicinally valuable benzyl isoquinoline alkaloid. 2,3,5,6-Tetramethoxyaporphine can be isolated from the yellow hornpoppy, Glaucium flavum Cr. (Fam. Papaveraceae).

(±)-Coclaurine is a natural product that can be found in Roemeria refracta. (±)-Coclaurine exhibits antioxidative activity and cardiovascular effects.

1-Methoxyallocryptopine is a natural product that can be isolated from Papaver curviscapum.

Dihydrochelirubine is an alkaloid which can be found in roots of macleaya cordata.

Corydamine, 3-arylisoquinoline alkaloid, is a potent DNA topoisomerase I/II inhibitor. Corydamine has anti-cancer activity.

Hyperectumine exhibits moderate anti-inflammatory activity via suppression of LPS-activated inflammatory mediators in RAW 264.7 macrophage cells.

Bis(dihydrochelerythrinyl)amine possesses anti-bacteria activity.

Norchelerythrine is an alkaloid isolated from the roots of Zanthoxylum capense with antibacterial activity against gram-positive and gram-negative bacteria. Norchelerythrine exhibits inhibitory activity against Staphylococcus aureus, Pseudomonas aeruginosa, and Enterococcus faecalis and Escherichia coli with MIC values >50 µg/mL.