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Cat. No.: HY-N0924B

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(-)-Stylopine

(Synonyms: (S)-Tetrahydrocoptisine)

(-)-Stylopine ((S)-Tetrahydrocoptisine) is an enantiomer of Stylopine (HY-N0924). Stylopine is a major alkaloid component of the leaf of Chelidonium majus.

For research use only. We do not sell to patients.

CAS No.: 84-39-9
Formula: C₁₉H₁₇NO₄
Molecular Weight:323.34

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (268 KB)

(-)-Stylopine Chemical Structure

CAS No.: 84-39-9

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Biological Activity
- Description
- Cellular Effect
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

Description

(-)-Stylopine ((S)-Tetrahydrocoptisine) is an enantiomer of Stylopine (HY-N0924). Stylopine is a major alkaloid component of the leaf of Chelidonium majus^[1].

Cellular Effect

Cell Line	Type	Value	Description	References
RAW264.7	IC₅₀	>50 μM Compound: 2	Antiinflammatory activity in mouse RAW264.7 cells assessed as inhibition of LPS-induced nitric oxide production after 24 hrs by griess assay Antiinflammatory activity in mouse RAW264.7 cells assessed as inhibition of LPS-induced nitric oxide production after 24 hrs by griess assay	[PMID: 22024033]

Chemical Information

CAS No. 84-39-9
Molecular Weight 323.34
Formula C₁₉H₁₇NO₄
SMILES

[H][C@@]12CC(C=C3)=C(C4=C3OCO4)CN1CCC5=C2C=C6OCOC6=C5
Synonyms

(S)-Tetrahydrocoptisine
Structure Classification
- Alkaloids
- Isoquinoline Alkaloids
Initial Source
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (268 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Jang SI, et al. Stylopine from Chelidonium majus inhibits LPS-induced inflammatory mediators in RAW 264.7 cells. Arch Pharm Res. 2004 Sep;27(9):923-9. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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