1. GPCR/G Protein
  2. Glucocorticoid Receptor

ORIC-101 

Cat. No.: HY-112710
Handling Instructions

ORIC-101 is a highly potent and selective glucocorticoid receptor antagonist, with an EC50 of 5.6 nM. Anti-cancer activity.

For research use only. We do not sell to patients.

ORIC-101 Chemical Structure

ORIC-101 Chemical Structure

CAS No. : 2222344-98-9

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  • Biological Activity

  • Technical Information

  • Purity & Documentation

  • References

Description

ORIC-101 is a highly potent and selective glucocorticoid receptor antagonist, with an EC50 of 5.6 nM. Anti-cancer activity.

IC50 & Target

EC50: 5.6 nM (Glucocorticoid receptor)[1]

In Vitro

ORIC-101 shows markedly reduced androgen receptor agonism (EC50, 2500 nM) and CYP2C8 and CYP2C9 inhibition profiles[1].

References
Molecular Weight

501.74

Formula

C₃₄H₄₇NO₂

CAS No.

2222344-98-9

SMILES

CN(C(C)C)C1=CC=C([[email protected]@H]2[[email protected]@]([[email protected]](CC3)([H])C(CC4)=CC3=O)([H])[[email protected]]4([H])[[email protected]@](CC[[email protected]]5(C#CC(C)(C)C)O)([H])[[email protected]]5(C)C2)C=C1

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Shipping

Room temperature in continental US; may vary elsewhere

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Product Name:
ORIC-101
Cat. No.:
HY-112710
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ORIC-101

Cat. No.: HY-112710