1. Immunology/Inflammation
  2. PD-1/PD-L1

PD1-IN-2 

Cat. No.: HY-101098
Handling Instructions

PD1-IN-2 is a PD1 signaling pathway inhibitor, which acts as an immunomodulator.

For research use only. We do not sell to patients.

PD1-IN-2 Chemical Structure

PD1-IN-2 Chemical Structure

CAS No. : 1673534-97-8

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  • Biological Activity

  • Technical Information

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  • References

Description

PD1-IN-2 is a PD1 signaling pathway inhibitor, which acts as an immunomodulator.

IC50 & Target

PD1[1]

In Vitro

PD1-IN-2 (Compound 25) is a PD1 signaling pathway inhibitor, which acts as an immunomodulator. PD1-IN-2 (100 nM) rescue 91% percent of the anti-CD3/CD28 stimulated splenocytes[1].

Solvent & Solubility
In Vitro: 

10 mM in DMSO

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.8795 mL 14.3976 mL 28.7952 mL
5 mM 0.5759 mL 2.8795 mL 5.7590 mL
10 mM 0.2880 mL 1.4398 mL 2.8795 mL
*Please refer to the solubility information to select the appropriate solvent.
References
Molecular Weight

347.28

Formula

C₁₁H₁₇N₅O₈

CAS No.

1673534-97-8

SMILES

O=C(N[[email protected]@H](CO)C(O)=O)N[[email protected]](C1=NC([[email protected]@H](N)CO)=NO1)CC(O)=O

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Shipping

Room temperature in continental US; may vary elsewhere

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The molarity calculator equation

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

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Product Name:
PD1-IN-2
Cat. No.:
HY-101098
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PD1-IN-2

Cat. No.: HY-101098