2. Inflammation/Immunology

Inflammation/Immunology

Inflammation/Immunology

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The diseases caused by disorders of the immune system fall into two broad categories: immunodeficiency and autoimmunity. Immunotherapy is also often used in the immunosuppressed (such as HIV patients) and people suffering from other immune deficiencies or autoimmune diseases. This includes regulating factors such as IL-2, IL-10, IFN-α. Infection with HIV is characterized not only by development of profound immunodeficiency but also by sustained inflammation and immune activation. Chronic inflammation as a critical driver of immune dysfunction, premature appearance of aging-related diseases, and immune deficiency.

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-N17888
    Ephemeranthol A 135545-86-7 98%
    Ephemeranthol A is a phenanthrene compound with anticancer and anti-inflammatory activities. Ephemeranthol A exerts significant anti-inflammatory effects in macrophages by inhibiting the NF-κB and MAPK signaling pathways. Ephemeranthol A induces apoptosis and inhibits metastasis of lung cancer cells by suppressing the FAK/Akt signaling and EMT processes. Ephemeranthol A can be used for the research of acute and chronic inflammatory diseases and non-small cell lung cancer.
    Ephemeranthol A
  • HY-N17889
    2,8-Dihydroxy-1-methoxyanthracene-9,10-dione 2765538-19-8
    2,8-Dihydroxy-1-methoxyanthracene-9,10-dione is an anthraquinone that can be found in the roots of Morinda officinalis How.
    2,8-Dihydroxy-1-methoxyanthracene-9,10-dione
  • HY-N17890
    Bletimalate D
    Bletimalate D is a 2-isobutylmalate found in the tubers of Bletilla striata. Bletimalate D shows no significant anti-pulmonary fibrosis activity and has cytotoxicity.
    Bletimalate D
  • HY-N17891
    Loddigesiinol A 1252577-62-0
    Loddigesiinol A is a phenanthrene compound found in Dendrobium loddigesii. Loddigesiinol A acts as a DPPH radical scavenger with an IC50 of 26.1 μM. Loddigesiinol A also inhibits nitric oxide production. Loddigesiinol A is applicable to inflammation-related research.
    Loddigesiinol A
  • HY-N17906
    Bletimalate C
    Bletimalate C is a 2-isobutyl malate ester present in the tubers of Bletilla striata. Bletimalate C potently inhibits the production of total Collagen in TGF-β1-activated NIH/3T3 cells, with an IC50 of 22.16 μM. Bletimalate C can be used for the research of pulmonary fibrosis.
    Bletimalate C
  • HY-N17908
    Viscumneoside V 119016-92-1 98.24%
    Viscumneoside V is a plant-derived anti-inflammatory agent present in Viscum album var. coloratum. Viscumneoside V inhibits the expression of MCP-1 and promotes the production of RANTES in LPS-stimulated immune cells. Viscumneoside V can be used for research related to skin rashes.
    Viscumneoside V
  • HY-N17909
    Broussin 76045-50-6
    Broussin ((S)-7-hydroxy-4'-methoxyflavane) is a flavane compound present in the branches and twigs of Broussonetia papyrifera. Broussin shows no significant antioxidant activity.
    Broussin
  • HY-N17919
    Salviifoside A 1175539-71-5
    Salviifoside A is a phenolic glycoside found in the leaves of Alangium salviifolium. Salviifoside A inhibits LPS (HY-D1056)-induced nitric oxide and prostaglandin E2 production in macrophages without affecting cell viability.
    Salviifoside A
  • HY-N17961
    Kalopanaxsaponin I 843668-13-3 98%
    Kalopanaxsaponin I (Septemloside I) is an oleanane-type triterpenoid that exists in the fruits of Stauntonia brachyanthera. Kalopanaxsaponin I inhibits LPS (HY-D1056)-induced nitric oxide production in macrophages, with a IC50 of 80.25 μM.
    Kalopanaxsaponin I
  • HY-N17976
    Scrophenoside A 705931-84-6
    Scrophenoside A (compound 1) is a phenyl glycoside found in the stems of Picrorhiza scrophulariiflora.Scrophenoside A exhibits anti-asthma activity.Scrophenoside A can be used for the research of asthma.
    Scrophenoside A
  • HY-N17985
    Kalopanaxsaponin H 119742-55-1 98%
    Kalopanaxsaponin H is an hederagenin glycoside (saponin) with no hypoglycemic activity upon intraperitoneal injection. Kalopanaxsaponin H can be metabolized by human intestinal bacteria into Kalopanaxsaponin I, Kalopanaxsaponin A, hederagenin 3-O-α-L-arabinopyranoside and hederagenin, among which Kalopanaxsaponin I and hederagenin are the main metabolites. Kalopanaxsaponin H is isolated from the stem bark of Kalopanax pictus and is used in diabetes-related research.
    Kalopanaxsaponin H
  • HY-N17989
    Acetylregaloside C 1585019-84-6
    Acetylregaloside C is a natural compound that can be extracted from Madonna Lily (Lilium candidum L.). Acetylregaloside C exhibits antioxidant properties and has the effect of promoting the production of α-amylase.
    Acetylregaloside C
  • HY-N17992
    Gypenoside UL5 1443433-27-9 98%
    Gypenoside UL5 (Compound UL5) is a dammarane-type triterpene saponin found in Gynostemma pentaphyllum. Gypenoside UL5 shows liver injury-inhibiting, anti-inflammatory and antioxidant properties. Gypenoside UL5 can be used for the research of hepatitis, fatty liver, and liver fibrosis.
    Gypenoside UL5
  • HY-N18001
    Plantanone A 2174008-34-3
    Plantanone A is a COX inhibitor with an IC50 of 33.37 μM against ovine COX-1 and an IC50 of 46.16 μM against ovine COX-2. Plantanone A exhibits weak DPPH radical scavenging activity (IC50: 467.7 μM). Plantanone A can be used in the research of inflammation-related diseases.
    Plantanone A
  • HY-N18011
    Opuntioside I 497179-09-6
    Opuntioside I is a glycoside found in the fresh stems of Opuntia dillenii. Opuntioside I shows weak radicals scavenging activity.
    Opuntioside I
  • HY-N18012
    Pratialin B 539856-79-6
    Pratialin B is a C14-polyacetylenol glycoside analog found in the roots of Codonopsis pilosula. Pratialin B exhibits weak inhibitory activity against LPS (HY-D1056)-induced NO production.
    Pratialin B
  • HY-N18018
    Tetrahydroswertianolin 189289-76-7 98%
    Tetrahydroswertianolin (Compound 1) is a tetrahydroxyxanthone glycoside that can be isolated from the whole plant of Swertia japonica Makino. Tetrahydroswertianolin reduces the elevated blood ALT levels in mice with immune-induced liver injury and exhibits protective activity against liver injury. Tetrahydroswertianolin can be used in studies related to anthelmintic, antipyretic and immune-induced liver injury.
    Tetrahydroswertianolin
  • HY-N18020
    Saurufuran A 425368-86-1 98%
    Saurufuran A is a PPARγ agonist with an EC50 of 16.7 μM. Saurufuran A is applicable to research related to type 2 diabetes, inflammatory diseases and certain cancers.
    Saurufuran A
  • HY-N18025
    Kaempferol 3-O-(2G-glucosylrutinoside)-7-O-glucoside 131559-50-7
    Kaempferol 3-O-(2G-glucosylrutinoside)-7-O-glucoside is an anti-inflammatory agent. Kaempferol 3-O-(2G-glucosylrutinoside)-7-O-glucoside exerts significant anti-inflammatory effects in LPS (HY-D1056)-induced RAW 264.7 macrophages by inhibiting the NF-κB, MAPK and Akt signaling pathways, thereby reducing the production of inflammatory mediators (NO, PGE2) and pro-inflammatory cytokines (TNF-α, IL-1β, IL-6).
    Kaempferol 3-O-(2G-glucosylrutinoside)-7-O-glucoside
  • HY-N18028
    20(22Z)-Ginsenoside Rh4 342632-88-6
    20(22Z)-Ginsenoside Rh4 is a rare ginsenoside with antitumor, anti-inflammation, and anti-diabetic activities.20(22Z)-Ginsenoside Rh4 can be found in Panax ginseng.
    20(22Z)-Ginsenoside Rh4
Cat. No. Product Name / Synonyms Application Reactivity