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Cat. No.: HY-W272207

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AChE/BChE-IN-31

AChE/BChE-IN-31 (Compound 3c) is a cholinesterase inhibitor. AChE/BChE-IN-31 exhibits certain inhibitory activity against hAChE and eqBChE. AChE/BChE-IN-31 also possesses antioxidant properties with an IC₅₀ value of 105.04 μM against DPPH. AChE/BChE-IN-31 can be used in the research of diseases such as Alzheimer’s disease.

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CAS No.: 6338-81-4
화학식: C₁₆H₁₄O₃
분자량:254.29

보관:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (265 KB)

AChE/BChE-IN-31 Chemical Structure

CAS No.: 6338-81-4

Amount: USD 0.00

* 장바구니에 담기 전 물품의 수량을 선택해 주십시오.

Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- 제품 설명
- Cellular Effect
Chemical Information
순도&문서
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

제품 설명

All Cholinesterase (ChE) Isoforms :

AChE
BChE

Cellular Effect

Cell Line	Type	Value	Description	References
CCRF-CEM	IC₅₀	5.9 μM Compound: 14	Concentration required to inhibit 50% growth of Human CEM T-lymphocytes cells Concentration required to inhibit 50% growth of Human CEM T-lymphocytes cells	[PMID: 9544201]
K562	IC₅₀	9.9 μM Compound: 2uu	Antiproliferative activity against human K562 cells after 5 days by MTT assay Antiproliferative activity against human K562 cells after 5 days by MTT assay	[PMID: 19837593]
L1210	IC₅₀	32.2 μM Compound: 14	Concentration required to inhibit 50% growth of L1210 leukemia cells Concentration required to inhibit 50% growth of L1210 leukemia cells	[PMID: 9544201]
P388	IC₅₀	8.7 μM Compound: 14	Inhibition of proliferation of murine P388 cells Inhibition of proliferation of murine P388 cells	[PMID: 9544201]

Chemical Information

CAS No. 6338-81-4
분자량 254.29
화학식 C₁₆H₁₄O₃
SMILES

O=C(C=CC1=CC=C(OC)C=C1)C2=CC=C(O)C=C2
선적

Room temperature in continental US; may vary elsewhere.
보관

Please store the product under the recommended conditions in the Certificate of Analysis.

순도&문서

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (265 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Kumar H, et al. Design, Synthesis, and biological evaluation of pyrazolo-benzothiazole derivatives as a potential therapeutic agent for the treatment of Alzheimer’s disease. Medicinal Chemistry Research, 2022, 31(11): 1931-1947.

Calculators

몰농도 계산기

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

농도 희석 계산기

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Bioz

Keywords

MOQ

Minimum order quantity

100 mg

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Other size

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Amount: USD 0.00

Biological Activity
- 제품 설명
Chemical Information
순도&문서
References

상품명:
Cat. No.:
수량:
MCE Japan Authorized Agent:

상품명:
CAS No.:
Species:
Purity:
수량:

AChE/BChE-IN-31

All Cholinesterase (ChE) Isoforms