AChE/BChE-IN-31
AChE/BChE-IN-31 (Compound 3c) is a cholinesterase inhibitor. AChE/BChE-IN-31 exhibits certain inhibitory activity against hAChE and eqBChE. AChE/BChE-IN-31 also possesses antioxidant properties with an IC50 value of 105.04 μM against DPPH. AChE/BChE-IN-31 can be used in the research of diseases such as Alzheimer’s disease.
For research use only. We do not sell to patients.
- CAS No.: 6338-81-4
- Formula: C16H14O3
- Molecular Weight:254.29
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
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Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| CCRF-CEM | IC50 |
5.9 μM
Compound: 14
|
Concentration required to inhibit 50% growth of Human CEM T-lymphocytes cells
Concentration required to inhibit 50% growth of Human CEM T-lymphocytes cells
|
[PMID: 9544201] |
| K562 | IC50 |
9.9 μM
Compound: 2uu
|
Antiproliferative activity against human K562 cells after 5 days by MTT assay
Antiproliferative activity against human K562 cells after 5 days by MTT assay
|
[PMID: 19837593] |
| L1210 | IC50 |
32.2 μM
Compound: 14
|
Concentration required to inhibit 50% growth of L1210 leukemia cells
Concentration required to inhibit 50% growth of L1210 leukemia cells
|
[PMID: 9544201] |
| P388 | IC50 |
8.7 μM
Compound: 14
|
Inhibition of proliferation of murine P388 cells
Inhibition of proliferation of murine P388 cells
|
[PMID: 9544201] |
Chemical Information
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CAS No. 6338-81-4
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Molecular Weight 254.29
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Formula C16H14O3
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SMILES
O=C(C=CC1=CC=C(OC)C=C1)C2=CC=C(O)C=C2
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Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)