Others

(Rac)-16:0 PI(5)P-d₅ (ammonium) is deuterium labeled (Rac)-16:0 PI(5)P (ammonium).

17:0-14:1 PC-d₅ is deuterium labeled 17:0-14:1 PC.

17:0-18:1 PE-d₅ is deuterium labeled 17:0-18:1 PE.

17:0-16:1 PE-d₅ is deuterium labeled 17:0-16:1 PE.

15:0-18:1-15:0 TG-d₅ is deuterium labeled 15:0-18:1-15:0 TG.

16:0 Coenzyme A-d₄ is deuterium labeled 16:0 Coenzyme A.

C26 D,L-Carnitine-d₉ is deuterium labeled C26 D,L-Carnitine.

24:1 SM (d18:1/24:1)-d₉ is deuterium labeled 24:1 SM (d18:1/24:1).

Totrombopag is an orally effective thrombopoietin receptor (TpoR) agonist. By activating TpoR, Totrombopag initiates an intracellular signaling cascade mediated by JAK2 kinase and the transcription factor Stat5, a signaling process that is the primary mechanism regulating megakaryocyte growth and differentiation into platelets. Totrombopag can be used to study platelet production and megakaryocyte biology.

Cathepsin K inhibitor 6 (compound 19) is an inhibitor of cathepsin K (Cat K) with an IC₅₀ of 17 nM. Cathepsin K inhibitor 6 also has inhibitory effects on other isoforms, with IC₅₀s of 0.05 μM (Cat L) and 0.3 μM (Cat B), respectively.

6-Epi-doxycycline is the C-6 epimer of Doxycycline (HY-N0565), formed as a degradation impurity through epimerization of Doxycycline under abnormal conditions (e.g., high temperature, pH changes, or humidity). 6-Epi-doxycycline is commonly used for the detection and analysis of impurity levels in pharmaceutical formulations.

Disialo-Asn (Sialylglycoasparaginate) is an asparagine oligosaccharide. Disialo-Asn can be used for nucleic acid modification.

ASO 556089 (with PS modification) sodium is the PS-modified version of ASO 556089 (HY-148688). ASO 556089 sodium is a 16 nucleotide length gapmer (3-10-3) that targets the human and mouse long non-coding RNA MALAT1, with the sequence: 5’-GmCATTmCTAATAGmCAGmC-3’.

3-Deoxy-D-manno-2-octulosonic acid (ammonium), 97% can be used for immunomodulation and for studying bacterial lipopolysaccharides (LPS).

Bedaquinoline impurity 1 is an impurity of Bedaquinoline.

(R,R)-VRT-534 is the (R,R)-enantiomer of VRT-534 (HY-149318). VRT-534 (Compound 3) is a chemical chaperone targeting connexin 26 (Cx26). Vrt-534 exhibits dose-responsive binding to recombinant WT Cx26 and mutant Cx26 K188N with EC₅₀s of 19 and 5 μM, respectively. Vrt-534 can be used in research related to hearing impairment.

PAP-IN-1 (compound 28) is an inhibitor of purple acid phosphatases (PAPs), a ubiquitous binuclear metallohydrolase. PAP-IN-1 inhibits mammalian PAP with K_i value of 168 nM. PAP-IN-1 targets to pig PAP with K_ic value of 0.17 μM. PAP inhibitors can be used for research of anti-osteoporotic drugs.

Lipid 1 is an ionizable amino lipid used for the generation of Lipid nanoparticles (LNPs).

Lipid 6 is an ionizable amino lipid. Lipid 6 can be used to synthesize lipid nanoparticles. Lipid 6 can be used in RNA delivery research.

1,4-Butanediol mononitrate-d₈ is the deuterium labeled 1,4-Butanediol mononitrate.