AMPK Antagonist
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Tezampanel etibutil
0 ImagesReferencia número: HY-176297No. CAS: 620113-98-6
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THR-β agonist 12
0 ImagesReferencia número: HY-184939No. CAS: 3063509-17-8THR-β agonist 12 is an orally active, potent, and highly selective thyroid hormone receptor β (THR-β) agonist (EC50 = 36 nM). THR-β agonist 12 shows no significant activity against THRα and exhibits no cardiotoxicity in vivo. THR-β agonist 12 inhibits lipid synthesis by activating the AMPK-ACC-SREBP1 signaling axis. THR-β agonist 12 can be used on research into metabolic dysfunction-associated steatohepatitis (MASH) and related metabolic diseases.
