2. Signaling Pathways
  3. Cell Cycle/DNA Damage
  4. APC
  5. APC Substrate

APC Substrate

APC Substrates (2):

Cat. No. Product Name Effect Purity
  • HY-122142A
    Pyr-​Pro-​Arg-​pNA (hydrochloride)
    		Substrate 99.24%
    Pyr-​Pro-​Arg-​pNA (S-2366) hydrochloride is a chromogenic peptidyl substrate, and a noncompetitive inhibitor that occupies the active sites of FXIa and FXIa-LC to block factor IX activation. Pyr-​Pro-​Arg-​pNA hydrochloride functions as a hydrolyzable substrate for FXIa’s catalytic domain, human APC, murine APC, and purified plasma kallikrein.
  • HY-122142
    Pyr-​Pro-​Arg-​pNA
    		Substrate
    Pyr-​Pro-​Arg-​pNA (S-2366) is a chromogenic peptidyl substrate, and a noncompetitive inhibitor that occupies the active sites of FXIa and FXIa-LC to block factor IX activation. Pyr-​Pro-​Arg-​pNA functions as a hydrolyzable substrate for FXIa’s catalytic domain, human APC, murine APC, and purified plasma kallikrein.